Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients.

NCT05353608 | Completed

• 1 other identifier: SCINTI-COVID (29BRC21.0143)
• Study Type: observational
• Target: 183
• Locations: 1 country
• Sites: 2

Brief Summary

A frequent complication of COVID-19 disease is pulmonary embolism (PE). Lung ventilation/perfusion (V/P) scintigraphy is a well-established test for PE diagnosis. The test is interpreted based on the recognition of wedge shaped perfusion mismatched defects. However, the ventilation procedure increases the potential risk of contamination by the aerosol secretion and the expired air. A variety of strategies have been proposed in the nuclear medicine literature regarding performance of lung ventilation scintigraphy in COVID-19 patients with suspected acute PE. However, there is currently no factual data in this specific population to support recommendations to the nuclear medicine community. The aim of this study was to assess the role of ventilation imaging when performing lung scintigraphy for suspected PE in COVID-19 patients.

Conditions

Pulmonary Embolism; COVID-19

Keywords

Lung scintigraphy

Outcome Measures

Primary Outcomes (1)

• PE diagnosis on lung scintigraphy without the ventilation scan.

  Percentage of scans for which the diagnostic conclusion of the lung scan would have been different when omitting the ventilation scan

  1 day

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COVID-19 patients who underwent lung scintigraphy for suspected PE.

You may qualify if:

• Patients with suspected COVID-19 disease
• Referred for lung scintigraphy for suspected acute PE

You may not qualify if:

• Patient under guardianship or curatorship
• Patient deprived of liberty by an administrative or judicial decision
• Inability or refuse to give consent

Sponsors & Collaborators

• University Hospital, Brest: lead

Study Sites (2)

CHRU de Brest

Brest, 29609, France

Location

Cnetre Jean-Perrin

Clermont-Ferrand, France

Location

MeSH Terms

Conditions

Pulmonary Embolism; COVID-19

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Embolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 27, 2022
• First Posted: April 29, 2022
• Study Start: April 30, 2021
• Primary Completion: May 31, 2021
• Study Completion: May 31, 2021
• Last Updated: August 9, 2024

Record last verified: 2022-04

Locations

FR (2)