NCT05352581

Brief Summary

The BD Veritor™ System is a rapid test that is testing for both COVID-19 and for Influenza This study will try to determine if the BD Veritor™ system can assist in the diagnosis of someone who has upper respiratory infection symptoms. There is both an At-Home self test and test completed by a health care professional that will be completed during this study.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,146

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2022

Shorter than P25 for all trials

Geographic Reach
3 countries

17 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 11, 2022

Completed
18 days until next milestone

First Posted

Study publicly available on registry

April 29, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

July 21, 2022

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2023

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 14, 2023

Completed
Last Updated

June 7, 2023

Status Verified

June 1, 2023

Enrollment Period

8 months

First QC Date

April 11, 2022

Last Update Submit

June 6, 2023

Conditions

Keywords

SARS COV 2Influenza

Outcome Measures

Primary Outcomes (2)

  • Diagnostic accuracy of the BD Veritor At-Home Assay

    Positive percent agreement of the BD Veritor At-Home Assay compared to an FDA cleared/approved RT-PCR Assay

    Immediately after specimen collection

  • Diagnostic accuracy of the BD Veritor Professional Assay

    Positive percent agreement of the BD Professional Assay compared to an FDA cleared/approved RT-PCR Assay

    Immediately after specimen collection

Secondary Outcomes (2)

  • Ease of Use of the BD Veritor At-Home Assay

    Within 30 minutes of test completion

  • Ease of Use of the BD Professional Assay

    Within 1 day of first device use

Study Arms (1)

BD Veritor

Each subject will: Self collect a nasal swab for testing on the BD Veritor At-home test (test device) Have a clinician collected nasal swab for testing on the BD Veritor Professional Test (test device) Have a clinical collected nasal swab for testing on an FDA cleared/approved RT-PCR assay (control device)

Diagnostic Test: BD Veritor At-HomeDiagnostic Test: BD Veritor Professional

Interventions

BD Veritor At-HomeDIAGNOSTIC_TEST

BD Veritor At-Home rapid self testing

BD Veritor

BD Veritor Professional rapid test

BD Veritor

Eligibility Criteria

Age2 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Individuals presenting with symptoms of acute respiratory illness

You may qualify if:

  • \. Participants symptomatic of an acute respiratory illness within 7 DOSO
  • \. ≥2 years of age at the time of study participation
  • \. Symptomatic subjects with
  • a. Any one of the following symptoms (with or without additional symptoms):
  • i. Fever
  • \. Oral/temporal artery: ≥100.4 °F / ≥38.0 °C
  • \. Rectal/Ear: ≥101.2 °F / ≥38.5 °C
  • ii. Cough
  • iii. Malaise (fatigue/extreme tiredness)
  • b. Or two of the following symptoms:
  • i. Sore throat,
  • ii. Shortness of breath/difficult breathing
  • iii. Rhinorrhea (runny or stuffy nose),
  • iv. Myalgia,
  • v. Headache,
  • +3 more criteria

You may not qualify if:

  • \. Participants currently undergoing treatment and/or within the past thirty (30) days of the study, with medication to treat novel Coronavirus SARS-CoV-2 viral infections, which may include but is not limited to Remdesivir (Veklury)
  • \. Participants receiving convalescent plasma therapy for SARS-CoV-2.
  • \. Participants who have received antiviral medications for influenza within the previous 30 days.
  • \. Participants who have had a nasal wash or aspirate as part of their standard of care treatment on day of study visit.
  • \. The participant is currently receiving or has received within the past thirty (30) days of the study visit, an experimental biologic or drug including either treatment or therapy.
  • \. Participants who have been previously enrolled in the study.
  • \. History of frequent or difficult to control nosebleeds within the last fourteen (14) days.
  • \. Participants who have tested positive for Flu A/B or SARS-CoV-2 within the last 28 days (excluding the day of enrollment in the study).
  • \. Participants without the ability to read or write in the English Language
  • \. Participants with prior medical or laboratory training.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

CTMD Research

Coconut Creek, Florida, 33063, United States

Location

CTMD Research

Palm Springs, Florida, 33406, United States

Location

DBC Research

Pembroke Pines, Florida, 33029, United States

Location

CTMD Reserarch

Asheville, North Carolina, 28804, United States

Location

Kur Research - AFC Urgent Care

Easley, South Carolina, 29640, United States

Location

Kur Research - AFC Urgent Care

Powdersville, South Carolina, 29611, United States

Location

Kur Research - AFC Urgent Care

Seneca, South Carolina, 29678, United States

Location

Kur Research - Complete Health Partners

Hendersonville, Tennessee, 37075, United States

Location

Kur Research - Complete Health Partners

Nashville, Tennessee, 37209, United States

Location

University of the Sunshine Coast

Sippy Downs, Queensland, 4556, Australia

Location

Southern Clinical Trials - Totara

Auckland, 0600, New Zealand

Location

Optimal Clinical Trials

Auckland, 1010, New Zealand

Location

Southern Clinical Trials - Remuera

Auckland, 1050, New Zealand

Location

Lakeland Clinical Trials - Waikato

Hamilton, 3200, New Zealand

Location

Southern Clinical Trials - Tasman

Nelson, 7011, New Zealand

Location

Silverdale Medical Ltd

Silverdale, 0932, New Zealand

Location

Southern Clinical Trials - Wellington

Upper Hutt, 5018, New Zealand

Location

Biospecimen

Retention: SAMPLES WITH DNA

Self-collected and clinician collected nasal swabs

MeSH Terms

Conditions

Respiratory Tract InfectionsInfluenza, Human

Condition Hierarchy (Ancestors)

InfectionsRespiratory Tract DiseasesOrthomyxoviridae InfectionsRNA Virus InfectionsVirus Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2022

First Posted

April 29, 2022

Study Start

July 21, 2022

Primary Completion

March 9, 2023

Study Completion

April 14, 2023

Last Updated

June 7, 2023

Record last verified: 2023-06

Locations