NCT05345756

Brief Summary

The study compares use of intraoral technique for maxillary advancement and extra oral technique with hep of protocol called Alt-RAMEC which depends on repeated expansion and constriction of maxilla to help in maxillary protraction

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
22

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 26, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 26, 2022

Completed
5 days until next milestone

Study Start

First participant enrolled

May 1, 2022

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2023

Completed
Last Updated

April 26, 2022

Status Verified

April 1, 2022

Enrollment Period

7 months

First QC Date

March 26, 2022

Last Update Submit

April 19, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Maxillary skeletal changes

    using lateral cephalometric x-ray to measure maxillary skeletal changes using angular measurements in degrees (SNA)

    8 months

Secondary Outcomes (2)

  • Mandibular skeletal changes

    8 months

  • Maxillary and Mandibular dental changes

    8 months

Study Arms (2)

Intraoral Protraction Technique

EXPERIMENTAL

using intraoral appliance composed of modified lingual arch and miniscrews for indirect anchorage for maxillary protraction after Alt-RAMEC protocol using hybrid expander

Device: Intraoral protraction device

Extraoral Protraction Technique

ACTIVE COMPARATOR

using facemask for maxillary protraction after ALT-RAMEC protocol

Device: Extraoral protraction device

Interventions

Use of modified lingual arch with indirect anchorage from screws between lower lateral incisor and lower canine to protract maxilla after ALT-RAMEC protocol

Intraoral Protraction Technique

Facemask which is an extraoral appliance used for maxillary protraction

Extraoral Protraction Technique

Eligibility Criteria

Age9 Years - 13 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Male or Female Growing Patient ( CVM2-CVM3 )
  • Skeletal class III (ANB ≤ 0 , A-NV≤ -2 and wits appraisal \< -0.3mm)
  • Erupted upper and lower first permanent molars and permanent incisors
  • Reverse overjet up to -4 mm

You may not qualify if:

  • History of previous orthodontic treatment
  • Cleft lip/palate patients
  • Patients with habits that are detrimental to dental occlusion (thumb sucking, tongue thrusting).
  • Patients with syndromes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Oral and dental medicine - Cairo University

Cairo, Manial, 11553, Egypt

RECRUITING

Study Officials

  • Andrew Demian, BDS

    Cairo University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Andrew Demian, BDS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 26, 2022

First Posted

April 26, 2022

Study Start

May 1, 2022

Primary Completion

December 1, 2022

Study Completion

January 1, 2023

Last Updated

April 26, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations