Childhood Obesity, Lifestyle Interventions and Weight Development

NCT05345353 | Completed

• 1 other identifier: 2596
• Study Type: observational
• Target: 2,898
• Locations: 1 country
• Sites: 1

Brief Summary

Childhood obesity has been associated with increased risk of both continued excess body weight, development of non-communicable lifestyle diseases and impaired mental health. Approximately 800 children with obesity were treated with a municipality based family-centered lifestyle intervention in the time period 2010-2020. In the same time period, approximately 2000 children with obesity who did not receive any treatment have been identified. Our aim is to investigate the efficiency of the two interventions and compare those to children not receiving any treatment. We will use data from both the clinical visits at the municipality health care workers and data from Statistics Denmark.

Conditions

Pediatric Obesity

Keywords

Lifestyle Intervention; Long term follow-up; Weight developement

Outcome Measures

Primary Outcomes (1)

• Weight development as assessed by BMI z-score:

  The weight development will be assessed in all children, who participated in one of two different lifestyle interventions compared to children with no intervention. The weight development will also be assessed in subgroups of the cohort, such as children who did not completed the intervention or who not did participation in the exercise part of the interventions.

  The Aarhus Protocol: 1st of January 2010 to 1st of June 2020. The Randers Protocol: 1st of January 2014 to 1st of June 2020. No Intervention: 1st of January 2010 to 1st of June 2020.

Secondary Outcomes (1)

• Socioeconomic differences, subgroup differences

  Socioeconomic data will be assessed at the time of inclusion for each subject.

Study Arms (3)

The Aarhus Protocol, Aarhus municipality:

Children with obesity who participated in a family-centered multicomponent lifestyle intervention - The Aarhus Protocol, Aarhus Municipality

Behavioral: Fat For Fight (FFF), The Aarhus Protocol

The Randers Protocol, Randers municipality:

children with obesity who participated in a family-centered multicomponent lifestyle Intervention - The Randers Protocol: Randers Municipality

Behavioral: The Children's Obesity Clinic Treatment (TCOCT), The Randers Protocol

No intervention

Children with obesity who didn't participate in a lifestyle intervention delivered by the municipality.

Interventions

Fat For Fight (FFF), The Aarhus Protocol BEHAVIORAL

A multicomponent family-centered lifestyle intervention which included visits at home and weekly supervised physical activity. Intervention duration - one year maximum

The Aarhus Protocol, Aarhus municipality:

The Children's Obesity Clinic Treatment (TCOCT), The Randers Protocol BEHAVIORAL

A multicomponent family-centered lifestyle intervention which included repeatedly visits (up to 8 times / year). Intervention duration - three years maximum

The Randers Protocol, Randers municipality:

Eligibility Criteria

• Age: 4 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children with obesity, 4-18 years of age living in Aarhus or Randers municipality between 2010-2020. The children have either received treatment with a community based lifestyle intervention or received no treatment.

You may qualify if:

• Obesity (BMI z-score above the 99. percentile for gender and age)

You may not qualify if:

• No Obesity

Sponsors & Collaborators

• University of Aarhus: lead
• Aarhus Kommune: collaborator
• Randers Municipality, Denmark: collaborator

Study Sites (1)

Steno Diabetes Center Aarhus

Aarhus N, 8200, Denmark

Location

MeSH Terms

Conditions

Pediatric Obesity

Interventions

CD36 Antigens

Condition Hierarchy (Ancestors)

Obesity; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Platelet Membrane Glycoproteins; Membrane Glycoproteins; Glycoproteins; Glycoconjugates; Carbohydrates; Fatty Acid Transport Proteins; Membrane Transport Proteins; Carrier Proteins; Proteins; Amino Acids, Peptides, and Proteins; Membrane Proteins; Receptors, Cell Surface; Receptors, Immunologic; Scavenger Receptors, Class B; Receptors, Scavenger; Receptors, LDL; Receptors, Lipoprotein

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Medical Doctor, PhD student at Institute for Clinical Medicin, Health, AU

Study Record Dates

• First Submitted: April 19, 2022
• First Posted: April 25, 2022
• Study Start: February 1, 2021
• Primary Completion: February 1, 2022
• Study Completion: March 1, 2022
• Last Updated: April 29, 2022

Record last verified: 2022-04

Locations

DK (1)