Short-term Automated Longitudinal Analysis of Speech and Language in Cognitive Impairment
"Análisis Longitudinal Del Habla y Seguimiento a Corto Plazo de Las Facultades Cognitivas de Personas Mediante Una Serie de Pruebas: Lista de Palabras CERAD, Repite Los dígitos en Orden Inverso, TMTA-B, Prueba Del Reloj, Fluidez fonémica, comprensión Verbal Relaciones semánticas, y semánticas Alternas".
1 other identifier
interventional
196
1 country
1
Brief Summary
Validate speech analysis AI models:
- To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- To evaluate the correlation between automatically analyzed linguistic variables and a combination of standard measures of cognition.
- To assess short-term variability in language ability among older adults, and to assess which aspects of language vary during the study period.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2019
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 22, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
March 22, 2022
CompletedFirst Submitted
Initial submission to the registry
March 29, 2022
CompletedFirst Posted
Study publicly available on registry
April 22, 2022
CompletedMarch 25, 2026
March 1, 2026
3.2 years
March 29, 2022
March 24, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Pre-post variability of normal, MCI and dementia at both points of the study.
Through standard deviation of normal subjects, MCI and dementia, variations in language are measured by considering MMSE scores and the most significant variables of accexible's tests (image description test, phonetic verbal fluency test and semantic verbal fluency test).
Change from the baseline cognitive function at 9 months.
Secondary Outcomes (1)
Correlation between cognitive tests and language variables obtained by the platform.
Every 6 to 9 months
Other Outcomes (1)
Accexible's model performance.
Every 6 to 9 months
Interventions
Speech analysis to detect and monitor mild cognitive impairment
Eligibility Criteria
You may qualify if:
- Adult patients 55+ years of age with suspected MCI or diagnosis of dementia and obtains a score greater than 20 on the MMSE.
- Patients must have agreed to participate in the study and have voluntarily signed the informed consent.
- (Healthy) Participants without a diagnosis neurological, or psychiatric disorders. Or taking medication that can affect cognitive abilities.
You may not qualify if:
- To have received a diagnosis of a significant psychiatric disorder or other cognitive impairment not due to neurodegeneration.
- To have significant vision problems that would affect the ability to perceive visual stimuli.
- To have significant hearing problems that would affect the ability to understand verbal cues.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Accexiblelead
Study Sites (1)
Centro de Prevención de Deterioro Cognitivo
Madrid, Madrid, 28006, Spain
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 29, 2022
First Posted
April 22, 2022
Study Start
January 1, 2019
Primary Completion
March 22, 2022
Study Completion
March 22, 2022
Last Updated
March 25, 2026
Record last verified: 2026-03