Evaluation of Respiratory Function and Functional Capacity in Pediatric Patients With Chronic Kidney Disease (CKD)

NCT05339997 | Completed

• 1 other identifier: ırmak çavuşoğlu
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic kidney disease (CKD) is defined as a permanent abnormality in kidney structure or function that persists for more than 3 months (for example, glomerular filtration rate \[GFR\] \<60 mL/min/1.73 m2 or albuminuria ≥30 mg/24 hours) and, it effects the 8% to 16% of the population worldwide.In pediatric patients with CKD, exercise capacity begins to decline in stage 3 of the disease and progressively decreases in stage 5, in dialysis and transplant patients (4, 5). Reduction in respiratory muscle strength and six minute walk test (6MWT) is observed in patients with CKD treated with hemodialysis (HD).The aim in present study is to evaluate the relationship between functional capacity and respiratory functions in stage 1-5 pediatric chronic kidney disease patients.

Conditions

Chronic Kidney Diseases; Chronic Renal Disease; Chronic Renal Failure

Keywords

pediatric chronic kidney disease; pulmonary function; functional capacity

Outcome Measures

Primary Outcomes (1)

• 6 minute walk test

  its a submaximal exercise test. The 6MWT is carried out in a marked 30 meter corridor. Patients are asked to walk as quickly as possible. They can stop whenever they want. The distance walked is recorded in meters. And it is interpreted according to the reference values of healthy children.quicly as possible and the distance will be record in meter.

  during the procedure

Secondary Outcomes (1)

• pulmonary function test

  during the procedure

Interventions

6 minute walk test, OTHER

submaximal exercise test used to evaluate the functional capacity of patients

Also known as: pulmonary function tests

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Pediatric patients aged 5-18 years with stage 1-5 chronic kidney disease

You may qualify if:

• Being between the ages of 5-18, having stage I-V chronic kidney disease,
• Having chronic kidney disease for at least 6 months,
• Not having visual and hearing impairment

You may not qualify if:

• Presence of mental retardation,
• Insufficient Turkish communication, Inability to communicate,
• Having metabolic-neurological problems,
• Presence of cardiomyopathy, angina pectoris,
• Presence of orthopedic problem that will prevent standing and walking
• Cerebrovascular disease
• Patients will not be included in the study in the presence of metastatic carcinoma.

Sponsors & Collaborators

• Acibadem University: lead

Study Sites (1)

Acibadem Mehmet Ali Aydınlar University

Istanbul, 34752, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic; Kidney Failure, Chronic

Interventions

Respiratory Physiological Phenomena

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Circulatory and Respiratory Physiological Phenomena

Study Officials

• Irmak Çavuşoğlu, MSc

  Acıbadem Mehmet Ali Aydınlar University

  STUDY DIRECTOR

• Elif Esma Safran, MSc

  Acıbadem Mehmet Ali Aydınlar University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist physiotherapist-Lecturer

Study Record Dates

• First Submitted: April 14, 2022
• First Posted: April 21, 2022
• Study Start: February 15, 2022
• Primary Completion: June 30, 2022
• Study Completion: July 10, 2022
• Last Updated: July 25, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)