Functional Inspiratory Muscle Training in Chronic Kidney Disease

NCT04958759 | Completed

• 1 other identifier: KA-20086
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Effects of functional inspiratory muscle training by telerehabilitation on respiratory and peripheral functions, functional capacity, diaphragm thickness and mobility, posture, quality of life, cognitive function, fatigue, physical activity, endothelial function and aortic stiffness in patients with chronic kidney disease will be investigated.

Conditions

Chronic Kidney Diseases

Keywords

Respiratory muscle

Outcome Measures

Primary Outcomes (8)

• Respiratory muscle strength

  Respiratory muscle strength will be evaluated using mouth pressure device

  10 minutes

• Respiratory muscle endurance

  Respiratory muscle endurance will be evaluated using incremental load test

  10 minutes

• Pulmonary function

  Pulmonary functions will be evaluated using spirometry

  5 minutes

• Peripheral muscle strength

  Peripheral muscle strength will be evaluated using dynamometer

  5 minutes

• Endurance of trunk muscles

  Endurance of trunk muscles will be evaluated using plank, side plank, flexor endurance and pelvic bridge test

  10 minutes

• Lower extremity muscle endurance

  Lower extremity muscle endurance will be evaluated using sit-to-stand test

  1 minutes

• Functional capacity

  Functional capacity will be evaluated using six-minute walk test

  10 minutes

• Diaphragm thickness and mobility

  Diaphragm thickness and mobility will be evaluated using ultrasonography

  20 minutes

Secondary Outcomes (9)

• Balance

  5 minutes

• Static balance

  5 minutes

• Posture

  5 minutes

• Qol

  10 minutes

• Cognitive function

  5 minutes

Study Arms (3)

Functional Inspiratory Muscle Training Group

EXPERIMENTAL

Functional inspiratory muscle training in patients with chronic kidney disease

Other: Functional Inspiratory Muscle Training; Other: Inspiratory Muscle Training

Inspiratory Muscle Training Group

EXPERIMENTAL

Inspiratory muscle training in patients with chronic kidney disease

Other: Inspiratory Muscle Training

Control Group

EXPERIMENTAL

Breathing exercises in patients with chronic kidney disease

Other: Breathing exercises

Interventions

Functional Inspiratory Muscle Training OTHER

The inspiratory muscle training program will be consist of 4 weeks of foundation inspiratory muscle training and 6 weeks of functional inspiratory muscle training

Functional Inspiratory Muscle Training Group

Inspiratory Muscle Training OTHER

The inspiratory muscle training program will be consist of 10 weeks of foundation inspiratory muscle training

Functional Inspiratory Muscle Training Group; Inspiratory Muscle Training Group

Breathing exercises OTHER

The program will be consist of 10 weeks of breathing exercises

Control Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with chronic kidney disease not receiving dialysis
• Access to the online program
• Volunteering to participate in the research

You may not qualify if:

• Having a musculoskeletal problem
• Having decompensated diabetes
• Having uncontrolled hypertension

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University, Faculty of Physical Therapy and Rehabilitation

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Interventions

Breathing Exercises

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Merve Firat, MSc

  Hacettepe University

  PRINCIPAL INVESTIGATOR

• Naciye Vardar-Yagli, PhD

  Hacettepe University

  STUDY DIRECTOR

• Tolga Yildirim, MD

  Hacettepe University

  STUDY DIRECTOR

• Deniz İnal-İnce, Professor

  Hacettepe University

  STUDY CHAIR

• Melda Saglam, PhD

  Hacettepe University

  STUDY CHAIR

• Ebru Calik-Kutukcu, PhD

  Hacettepe University

  STUDY CHAIR

• Ahmet Hakan Ates, MD

  Hacettepe University

  STUDY CHAIR

• Selin Ardali-Duzgun, MD

  Hacettepe University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research assistant

Study Record Dates

• First Submitted: May 12, 2021
• First Posted: July 12, 2021
• Study Start: March 1, 2021
• Primary Completion: September 9, 2022
• Study Completion: May 3, 2023
• Last Updated: August 14, 2023

Record last verified: 2023-08

Locations

TU (1)