NCT05337605

Brief Summary

In this study, a comparison is made between two types of polyp resection methods (hand driven and motor driven morcellation). More specifically, the effects of the resection on symptoms such as abnormal uterine bleeding, and on the recurrence of polyps. The aim of the study is to find a superior method in terms of symptom relieve and polyp recurrence so this method can be used in gynaecological practice.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
87

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2022

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

April 4, 2022

Completed
16 days until next milestone

First Posted

Study publicly available on registry

April 20, 2022

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 8, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 8, 2022

Completed
Last Updated

July 13, 2023

Status Verified

July 1, 2023

Enrollment Period

7 months

First QC Date

April 4, 2022

Last Update Submit

July 12, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rate of recurrence of abnormal uterine blood loss (+ cause, treatment)

    Patient reported outcome by means of a questionnaire (yes/no, specify)

    1 to 4 years

Secondary Outcomes (9)

  • Rate of recurrence of other symptoms (abdominal pain, infections, back pain, other..) (+ cause, treatment)

    1 to 4 years

  • Recurrence interval (time to recurrence of endometrial polyp)

    1 to 4years

  • Number of patients with symptom relief after initial intervention (abdominal pain, abnormal uterine blood loss, other...)

    1 to 4years

  • Rate of occurrence of new symptoms after initial intervention (abdominal pain, abnormal uterine blood loss, infections, other...) (+ cause, treatment)

    1 to 4years

  • Rate of occurrence of new polyps (+ cause, treatment)

    1 to 4years

  • +4 more secondary outcomes

Study Arms (2)

Hand driven tissue removal system

Endometrial polyp removed by hysteroscopic hand-driven tissue removal system in a previous study.

Motor driven tissue removal system

Endometrial polyp removed by hysteroscopic motor-driven tissue removal system in a previous study.

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

women treated for endometrial polyps in earlier study

You may qualify if:

  • participation in earlier study

You may not qualify if:

  • N/A

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Catharina Ziekenhuis

Eindhoven, North Brabant, 5623 EJ, Netherlands

Location

Related Publications (1)

  • Van Geyte M, de Frenne A, Weyers B, Weyers S, van Vliet H, Hamerlynck T, van Wessel S. Manually driven versus motor driven hysteroscopic tissue removal system for polypectomy: Long-term results. Eur J Obstet Gynecol Reprod Biol. 2024 May;296:270-274. doi: 10.1016/j.ejogrb.2024.03.013. Epub 2024 Mar 12.

Study Officials

  • Tjalina Hamerlynck, Md, Phd

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 4, 2022

First Posted

April 20, 2022

Study Start

April 1, 2022

Primary Completion

November 8, 2022

Study Completion

November 8, 2022

Last Updated

July 13, 2023

Record last verified: 2023-07

Locations