Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation
1 other identifier
observational
40
0 countries
N/A
Brief Summary
To assess whether cardiac T1 mapping for detection of myocardial fibrosis enables preoperative identification of patients at risk for early left ventricular dysfunction after surgery of aortic regurgitation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jul 2016
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 29, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
March 13, 2020
CompletedFirst Submitted
Initial submission to the registry
April 11, 2022
CompletedFirst Posted
Study publicly available on registry
April 18, 2022
CompletedApril 18, 2022
April 1, 2022
3.2 years
April 11, 2022
April 15, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Native T1
Measured with MRI
baseline (Prior surgery)
Study Arms (1)
Patients prior to aortic valve surgery
Interventions
Eligibility Criteria
A total of 40 consecutive AR patients referred for aortic valve surgery were included.
You may qualify if:
- Consecutive patients with severe aortic regurgitation referred for aortic valve surgery were prospectively enrolled in the study.
You may not qualify if:
- history of coronary artery disease
- acute aortic valve disease (i.e., type A aortic dissection or infectious endocarditis)
- common contraindications for MRI such as severe obesity and metallic foreign bodies.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident
Study Record Dates
First Submitted
April 11, 2022
First Posted
April 18, 2022
Study Start
July 1, 2016
Primary Completion
August 29, 2019
Study Completion
March 13, 2020
Last Updated
April 18, 2022
Record last verified: 2022-04