Optimization of Sequences to Improve the Quality and Comfort of the Magnetic Resonance Imaging Examination

NCT05326581 | Recruiting

• 1 other identifier: JSY_2021_30
• Study Type: observational
• Target: 750
• Locations: 1 country
• Sites: 1

Brief Summary

The people included will carry out an MRI comprising the sequence currently used in routine care and the different variants of the sequence being tested, for the optimization of the parameters. The duration of the examination (or the extension of the examination planned as part of patient care) will be from a few minutes to an hour depending on the sequences to be optimized. Subjects who agree to research for more than 30 minutes in the MRI machine will be compensated with a multi-brand gift voucher worth 30 euros.

Conditions

Optimized MRI Sequences

Outcome Measures

Primary Outcomes (3)

• Quality of imagery

  Quality of imagery evaluated on a likert-type scale (range from : "very bad quality" to "very good quality") by two experts

  Baseline

• Presence or absence of radiological image artifact

  Presence/absence of radiological image artifact evaluated on a likert-type scale (range from : "major - impossible interpretation" to "none") by two experts

  Baseline

• Confidence in diagnosis

  Confidence in diagnosis evaluated on a likert-type scale (range from : "not confident" to "very confident") by two experts

  Baseline

Study Arms (2)

PATIENTS

patients benefiting from an MRI examination as part of their care

Device: mri

VOLUNTEERS

healthy volunteers among staff.

Device: mri

Interventions

mri DEVICE

The people included will carry out an MRI comprising the sequence currently used in routine care and the different variants of the sequence being tested, for the optimization of the parameters. The duration of the examination (or the extension of the examination planned as part of patient care) will be from a few minutes to an hour depending on the sequences to be optimized. Subjects who agree to research for more than 30 minutes in the MRI machine will be compensated with a multi-brand gift voucher worth 30 euros.

PATIENTS; VOLUNTEERS

Eligibility Criteria

• Age: 18 Months+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participation in the study will be offered to patients performing MRI imaging as part of the treatment as well as to healthy volunteers among the staff.

You may qualify if:

• Subject over 18 years old
• Consent to participate in the study
• Member of or beneficiary of a social security scheme
• For patients: benefiting from an MRI examination as part of their care
• For volunteers: Consent to be informed if an unexpected anomaly is revealed by the imaging.

You may not qualify if:

• Subject benefiting from a measure of legal protection
• Pregnant or breastfeeding women
• For volunteers: Contraindication to MRI (detailed contraindications questionnaire, THI score \>28 questionnaire, hearing sensitivity questionnaire grade \>1)

Sponsors & Collaborators

• Fondation Ophtalmologique Adolphe de Rothschild: lead

Study Sites (1)

Hôpital Fondation Adolphe de Rothschild

Paris, Paris, 75019, France

RECRUITING

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Julien Savatovksy, MD

  Fondation A. de Rothschild

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Amélie Yavchitz, MD

CONTACT

(0)148036454; ayavachitz@for.paris

Julien Savatovsky, MD

CONTACT

jsavatovsky@for.paris

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 18, 2022
• First Posted: April 13, 2022
• Study Start: May 23, 2022
• Primary Completion (Estimated): May 1, 2027
• Study Completion (Estimated): May 1, 2027
• Last Updated: January 5, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)