NCT05326022

Brief Summary

The study aiming to compare between the Microcurrent and Low-Level Laser Therapy on wound healing

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 23, 2022

Completed
21 days until next milestone

First Posted

Study publicly available on registry

April 13, 2022

Completed
15 days until next milestone

Study Start

First participant enrolled

April 28, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2022

Completed
Last Updated

April 13, 2022

Status Verified

April 1, 2022

Enrollment Period

5 months

First QC Date

March 23, 2022

Last Update Submit

April 6, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • levels of matrix metalloproteinases

    analyze by Enzyme-linked immunosorbent assay

    assessed at day 3 post operative

Secondary Outcomes (3)

  • levels of matrix metalloproteinases

    assessed at day 30 post operative

  • the tissue inhibitors of metalloproteinases

    assessed at day 3 post operative

  • the tissue inhibitors of metalloproteinases

    assessed at day 30 post operative

Study Arms (3)

medical therapy group

EXPERIMENTAL

formed of 20 patients to whom ordinary medical therapy as the pervious groups and placebo shame laser had been applied.

Other: Medical therapy

medical therapy and Microcurrent group

EXPERIMENTAL

formed of 20 patients to whom the microcurrent therapy had been applied with ordinary medical therapy.

Device: Microcurrent therapyOther: Medical therapy

medical therapy and Low-Level Laser Therapy group

EXPERIMENTAL

formed of 20 patients to whom the Low Level Laser Therapy had been applied with ordinary medical therapy.

Device: Low Level Laser TherapyOther: Medical therapy

Interventions

Microcurrent therapy

medical therapy and Microcurrent group

Laser therapy

medical therapy and Low-Level Laser Therapy group

Medical therapy

medical therapy and Low-Level Laser Therapy groupmedical therapy and Microcurrent groupmedical therapy group

Eligibility Criteria

Age10 Years - 50 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • patient recently undergo appendectomy

You may not qualify if:

  • patient with neurological disorders
  • patient with metabolic disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Dickinson LE, Gerecht S. Engineered Biopolymeric Scaffolds for Chronic Wound Healing. Front Physiol. 2016 Aug 5;7:341. doi: 10.3389/fphys.2016.00341. eCollection 2016.

    PMID: 27547189BACKGROUND

MeSH Terms

Interventions

Low-Level Light TherapyNutrition Therapy

Intervention Hierarchy (Ancestors)

Laser TherapyTherapeuticsPhototherapy

Study Officials

  • Nehad A. Abo-Zaid, PhD

    South Valley University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nehad A. Abo-Zaid, PhD

CONTACT

Mohammed E. Ali, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant professor of physical therapy

Study Record Dates

First Submitted

March 23, 2022

First Posted

April 13, 2022

Study Start

April 28, 2022

Primary Completion

September 30, 2022

Study Completion

October 30, 2022

Last Updated

April 13, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share