NCT05325931

Brief Summary

Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study. All subjects will be seen for a Screening/Dispensing Visit at which informed consent will be obtained and eligibility will be assessed. If subjects satisfy all eligibility criteria and none of the exclusion criteria, subjects will be fit and dispensed study lenses according to unique randomization schedules that will be provided to each Investigator If vision is unsatisfactory in the original dispensed lenses, additional lens powers may be trialed.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 25, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 28, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 28, 2022

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

April 1, 2022

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 13, 2022

Completed
Last Updated

April 13, 2022

Status Verified

April 1, 2022

Enrollment Period

1 month

First QC Date

April 1, 2022

Last Update Submit

April 12, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Visual Acuity

    Mean Binocular logMAR Visual Acuity at Distance (6m)

    One week

  • Near Visual Acuity

    Mean Binocular logMAR Visual Acuity at Near (40cm)

    One week

Study Arms (2)

kalifilcon A Daily Disposable Multifocal

EXPERIMENTAL

kalifilcon A Daily Disposable Multifocal Low Add Power (LA) and High Add Power (HA)

Device: kalifilcon A Daily Disposable Multifocal

samfilcon A for Presbyopia

ACTIVE COMPARATOR

B+L ULTRA for Presbyopia Low Add Power (LA) and High Add Power (HA)

Device: samfilcon A for Presbyopia

Interventions

kalifilcon A Daily Disposable Multifocal low add and high

kalifilcon A Daily Disposable Multifocal

Ultra for Presbyopia Low and High Add Contact Lenses

samfilcon A for Presbyopia

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be 40 years or older on the date the Informed Consent Form (ICF) is signed and have the capacity to read, understand and provide written voluntary informed consent.
  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Have no active ocular disease or allergic conjunctivitis.
  • Not be using any topical ocular medications.
  • Be willing and able to follow instructions.
  • Have signed a statement of informed consent.

You may not qualify if:

  • Participating in a conflicting study.
  • Considered by the Investigator to not be a suitable candidate for participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch site 1

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Presbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • Robert Steffen

    Bausch & Lomb Incorporated

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 1, 2022

First Posted

April 13, 2022

Study Start

February 25, 2022

Primary Completion

March 28, 2022

Study Completion

March 28, 2022

Last Updated

April 13, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations