Lung Recruitment Maneuvers for Postoperative Atelectasis Prevention After Idiopathic Adolescents' Scoliosis Correction

NCT05325463 | Completed DMC

• 1 other identifier: Atelectasis in scoliosis
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators hypothesized that an ultrasound-guided lung recruitment maneuvers would be more effective in preventing postoperative atelectasis than conventional alveolar recruitment after surgical correction of idiopathic adolescent scoliosis.

Conditions

Postoperative Atelectasis; Lung Recruitment; Scoliosis; Adolescence

Outcome Measures

Primary Outcomes (1)

• the incidence of atelectasis

  the incidence of postoperative atelectasis in post-anaesthesia care unit

  postoperative first 2 hours

Study Arms (2)

conventional

EXPERIMENTAL

Procedure: conventional lung recruitment

ultrasound- guided

ACTIVE COMPARATOR

Procedure: ultrasound- guided lung recruitment

Interventions

conventional lung recruitment PROCEDURE

The recruitment maneuver will be performed by pressure controlled mode maintaining a steady airway pressure of 15 cmH2O, with 5 cmH2O increments in positive end-expiratory pressure (PEEP) until a peak pressure of 30 cmH2O will be achieved. Each PEEP level will be maintained for 5 sec. The peak airway pressure will be maintained for 10 sec or five breaths and subsequently reduced, followed by maintenance with the previous ventilator settings.

conventional

ultrasound- guided lung recruitment PROCEDURE

The recruitment maneuver will be performed under ultrasound guidance until no collapsed lung area was visible. The strategy to increase the airway pressure will be the same as that for the conventional maneuver, although the maximal pressure limit was 40 cmH2O.

ultrasound- guided

Eligibility Criteria

• Age: 11 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients scheduled for elective correction of AIS
• aged between 10 and 25 years old
• American society of anesthesiologists (ASA) class I \& II
• both genders

You may not qualify if:

• Morbidly obese patients
• patients with previous thoracic surgery
• upper or lower airway infection within 2 weeks before the surgery
• abnormal preoperative chest x-ray findings including atelectasis, pneumothorax, pleural effusion or pneumonia

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Faculty of medicine, Tanta university

Tanta, El Gharbyia, 31111, Egypt

Location

MeSH Terms

Conditions

Scoliosis

Condition Hierarchy (Ancestors)

Spinal Curvatures; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: April 6, 2022
• First Posted: April 13, 2022
• Study Start: April 10, 2022
• Primary Completion: April 1, 2024
• Study Completion: April 30, 2024
• Last Updated: May 1, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)