Diabetes Registry Graz for Biomarker Research

NCT05324488 | Recruiting

• 1 other identifier: HS-2015-01
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

The Diabetes registry for biomarker research Graz is a prospective cohort-study including subjects with type 1 and type 2 diabetes, rare types of diabetes, obesity and dyslipidemia, aiming to collect data, blood and urine samples of all subjects on an annual basis.

Conditions

Type1diabetes; Type 2 Diabetes; Adiposity

Keywords

cohort study

Outcome Measures

Primary Outcomes (1)

• Biomarker identification

  Identification of biomarker panels that allow prediction of future micro- and macrovascular disease and events. Changes of these biomarkers over time in a selected, defined cohort will be reported.

  Over entire period of registry (20 years)

Secondary Outcomes (1)

• Biomarker validation

  Over entire period of registry (20 years)

Study Arms (7)

Type 1 Diabetes

Patients with diagnosed type 1 diabetes mellitus

Other: No intervention

Type 2 Diabetes

Patients with diagnosed type 2 diabetes mellitus

Other: No intervention

Adipositas

Obese patients with a BMI \> 30kg/m2

Other: No intervention

Lipid metabolism disorder

Patients with disorder of lipid metabolism

Other: No intervention

Type 3 Diabetes Mellitus

Patients with diagnosed type 3 diabetes mellitus

Other: No intervention

Maturity onset diabetes of the young (MODY)

Patients with diagnosed MODY

Other: No intervention

Late onset diabetes of the adult (LADA)

Patients with diagnosed LADA

Other: No intervention

Interventions

No intervention OTHER

In this registry no intervention is carried out

Adipositas; Late onset diabetes of the adult (LADA); Lipid metabolism disorder; Maturity onset diabetes of the young (MODY); Type 1 Diabetes; Type 2 Diabetes; Type 3 Diabetes Mellitus

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with different types of diabetes as well as obesity and lipid metabolism disorder are observed in this registry.

You may qualify if:

• years
• Informed consent has to be given in written form
• At least one of the following diseases:
• Type 1 diabetes
• Type 2 diabetes
• Type 3 diabetes
• Maturity onset diabetes of young (MODY)
• Late onset diabetes of the adult (LADA)
• Adipositas (BMI \> 30kg/m2)
• Lipid metabolism disorder

You may not qualify if:

• No written informed consent
• No willingness to participate in this registry

Sponsors & Collaborators

• Medical University of Graz: lead

Study Sites (1)

Medical University of Graz

Graz, 8010, Austria

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

Urinary, plasma and serum samples are collected for future analysis

MeSH Terms

Conditions

Diabetes Mellitus, Type 2; Obesity

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Overweight; Overnutrition; Nutrition Disorders; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Harald Sourij, MD

  Medical University of Graz

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Caren Sourij, MD

CONTACT

caren.sourij@medunigraz.at

Harald Sourij, MD

CONTACT

ha.sourij@medunigraz.at

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 20 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 29, 2021
• First Posted: April 12, 2022
• Study Start: October 21, 2015
• Primary Completion (Estimated): January 1, 2035
• Study Completion (Estimated): February 1, 2035
• Last Updated: July 7, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

AU (1)