NCT04130269

Brief Summary

People often experience the acute phase of a myocardial infarction as a stressful and traumatic event that seems lifethreatening. Such anxiety, pain and stress can lead to the development of posttraumatic stress disorder in the long run. Previous studies suggest that there might be a relevant percentage of people developing Posttraumatic Stress Disorder (PTSD) after a myocardial infarction. Posttraumatic stress disorder is a risk factor for the development of coronary heart disease. The goal of this study is to detect the percentage of people that develop symptoms of anxiety, stress, and PTSD after an acute myocardial infarction.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
18mo left

Started Apr 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress81%
Apr 2020Dec 2027

First Submitted

Initial submission to the registry

October 16, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 17, 2019

Completed
6 months until next milestone

Study Start

First participant enrolled

April 7, 2020

Completed
7.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 7, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 7, 2027

Last Updated

September 29, 2025

Status Verified

September 1, 2025

Enrollment Period

7.7 years

First QC Date

October 16, 2019

Last Update Submit

September 23, 2025

Conditions

Myocardial Infarction

Outcome Measures

Primary Outcomes (1)

  • PTSD

    Number of patients who develop PTSD

    6 months

Study Arms (1)

Patients with MCI

Patients with myocardial infarction (STEMI/NSTEMI) aged 19-90

Other: No intervention

Interventions

No interventionOTHER

Questionnaires, lab-run

Patients with MCI

Eligibility Criteria

Age19 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Men and women 19-90.

You may qualify if:

  • willingness to participate in the study
  • men and women 19-90
  • after myocardial infarctions
  • no psychiatric disease before myocardial infarction
  • no other severe disease influencing the immune system

You may not qualify if:

  • non-compliant patients (dementia, delirium)
  • steroid-therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University of Graz

Graz, Styria, 8036, Austria

RECRUITING

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Central Study Contacts

Andreas Baranyi, MD

CONTACT

004331638513612an.baranyi@medunigraz.at

Hans-Bernd Rothenhäusler, MD

CONTACT

004331638513612

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 16, 2019

First Posted

October 17, 2019

Study Start

April 7, 2020

Primary Completion (Estimated)

December 7, 2027

Study Completion (Estimated)

December 7, 2027

Last Updated

September 29, 2025

Record last verified: 2025-09

Locations

AU(1)