Intrahospital Transport in Patients With High-flow Nasal Oxygenation: Prospective Observational Study

NCT05311007 | Completed

• 1 other identifier: CHRO-2022-01
• Study Type: observational
• Target: 175
• Locations: 1 country
• Sites: 4

Brief Summary

High-flow nasal oxygen therapy is commonly used in intensive care unit (ICU). Intra-hospital transfer of critical patients is frequent: 1) to perform diagnostic 2) between emergency room or medical wards and ICU. During theses transfers, oxygenation should be continued. There is high-flow nasal oxygen therapy for transport using an external battery. This mode of operation in transport mode allows about 30-45 min of autonomy. Intra-hospital transport under high-flow nasal oxygen therapy has been previously described on children. The objective of this study is to evaluate the occurrence of complications during intra-hospital transports under high-flow nasal oxygen of critical patients.

Conditions

Critical Illness

Keywords

High-flow nasal oxygenation; intra-hospital transport; critical ill patients; intensive care units

Outcome Measures

Primary Outcomes (1)

• Incidence of severe adverse events during intra-hospital transport

  To evaluate the incidence of severe adverse events during intra-hospital transport of patients treated with high-flow nasal oxygen surpervised by an ICU staff. Severe adverse event is defined by the occurrence of intubation during transport or severe hypoxemia defined as pulse oxygen saturation (SpO2 \< 80%) or cardiorespiratory arrest.

  Up to 28 days

Secondary Outcomes (1)

• Incidence of minor adverse events during intra-hospital transport

  Up to 28 days

Interventions

Evaluation of the incidence and nature of adverse events OTHER

Evaluation of the incidence and nature of adverse events during intra-hospital transport of patients undergoing high-flow nasal oxygen therapy provided by intensive care units

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients requiring intra-hospital transfer on high-flow nasal oxygen therapy will be eligible to participate in the study

You may qualify if:

• Patient treated with high-flow nasal oxygen therapy before the intra-hospital transport prior to transport
• Requiring an intra-hospital transport (e.g., CT scan, OR, etc.) or inter-departmental transport supervised by the ICU team
• Nb: Once the patient is included in the study, any intra-hospital transport under high-flow nasal oxygen therapy will be analyzed until discharge from the intensive care unit and at until D28.

You may not qualify if:

• Under 18 years old
• Patient being under guardianship, tutorship or curatorship
• Pregnancy or breastfeeding
• Lack of social security number
• Refusal to participate in the study

Sponsors & Collaborators

• Centre Hospitalier Régional d'Orléans: lead

Study Sites (4)

Hospital Center of DAX

Dax, France

Location

CH de Martigues

Martigues, France

Location

CHU Orléans

Orléans, 45067, France

Location

CH Bretagne Atlantique vannes-Auray

Vannes, 56017, France

Location

Related Publications (1)

• Nay MA, Bisson A, Auvet A, Delbove A, Berrouba A, Kamel T, Desgrouas M, Boulain T. Intra-hospital transport of adult critically ill patients treated with high flow nasal cannula oxygen: a prospective observational multicenter study. Ann Intensive Care. 2025 Jul 8;15(1):93. doi: 10.1186/s13613-025-01502-7.

  PMID: 40629187 DERIVED

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mai-Anh NAY, Dr

  CHU d'Orléans

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 23, 2022
• First Posted: April 5, 2022
• Study Start: May 28, 2022
• Primary Completion: May 4, 2024
• Study Completion: May 4, 2024
• Last Updated: December 23, 2025

Record last verified: 2025-12

Locations

FR (4)