NCT05310474

Brief Summary

The purpose of this study is to study the efficacy of a remote range of motion monitor, the Knee Glider, alongside a patient engagement platform, Force Therapeutics, on clinical improvements and cost following primary TKA.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2022

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 14, 2021

Completed
4 months until next milestone

First Posted

Study publicly available on registry

April 5, 2022

Completed
25 days until next milestone

Study Start

First participant enrolled

April 30, 2022

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

April 14, 2022

Status Verified

April 1, 2022

Enrollment Period

8 months

First QC Date

December 14, 2021

Last Update Submit

April 6, 2022

Conditions

Outcome Measures

Primary Outcomes (37)

  • Baseline Patient Characteristics

    Intended to collect patient demographics, contact information, birth date, surgery date, age and other baseline demographic variables.

    Baseline

  • Knee Injury and Osteoarthritis Outcome Score (KOOS Jr.)

    Intended to elicit people's opinions about the difficulties they experience due to problems with their knee and covers aspects of pain, functional limitations and knee-related quality of life. KOOS, JR is scored by summing the raw response (range 0-28) and then converting it to an interval score using the table provided below. The interval score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.

    Baseline, 2 Weeks Post Op, 6 Weeks Post Op, 12 Weeks Post Op, 6 Months Post Op,

  • Knee Injury and Osteoarthritis Outcome Score (KOOS Jr.)

    Intended to elicit people's opinions about the difficulties they experience due to problems with their knee and covers aspects of pain, functional limitations and knee-related quality of life. KOOS, JR is scored by summing the raw response (range 0-28) and then converting it to an interval score using the table provided below. The interval score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.

    6 Weeks Post Op

  • Knee Injury and Osteoarthritis Outcome Score (KOOS Jr.)

    Intended to elicit people's opinions about the difficulties they experience due to problems with their knee and covers aspects of pain, functional limitations and knee-related quality of life. KOOS, JR is scored by summing the raw response (range 0-28) and then converting it to an interval score using the table provided below. The interval score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.

    12 Weeks Post Op

  • Knee Injury and Osteoarthritis Outcome Score (KOOS Jr.)

    Intended to elicit people's opinions about the difficulties they experience due to problems with their knee and covers aspects of pain, functional limitations and knee-related quality of life. KOOS, JR is scored by summing the raw response (range 0-28) and then converting it to an interval score using the table provided below. The interval score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.

    6 Months Post Op

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

    1. The WOMAC is a disease-specific tool used for people with hip or knee OA to measure physical function, pain, and stiffness in the past 48 hours. 2. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items). 3. Scores can be calculated for each subscale and a total score is calculated by adding all 3 subscale scores. Higher points signify higher levels of functional difficulty.

    Baseline

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

    1. The WOMAC is a disease-specific tool used for people with hip or knee OA to measure physical function, pain, and stiffness in the past 48 hours. 2. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items). 3. Scores can be calculated for each subscale and a total score is calculated by adding all 3 subscale scores. Higher points signify higher levels of functional difficulty.

    6 Weeks Post Op

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

    1. The WOMAC is a disease-specific tool used for people with hip or knee OA to measure physical function, pain, and stiffness in the past 48 hours. 2. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items). 3. Scores can be calculated for each subscale and a total score is calculated by adding all 3 subscale scores. Higher points signify higher levels of functional difficulty.

    12 Weeks Post Op

  • Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

    1. The WOMAC is a disease-specific tool used for people with hip or knee OA to measure physical function, pain, and stiffness in the past 48 hours. 2. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items). 3. Scores can be calculated for each subscale and a total score is calculated by adding all 3 subscale scores. Higher points signify higher levels of functional difficulty.

    6 Months Post Op

  • Veterans RAND 12 (VR-12)

    a. The Veterans RAND 12 Item Health Survey (VR-12) is a patient-reported global health measure that is used to assess a patient's overall perspective of their health.

    Baseline

  • Veterans RAND 12 (VR-12)

    The Veterans RAND 12 Item Health Survey (VR-12) is a patient-reported global health measure that is used to assess a patient's overall perspective of their health.

    6 Weeks Post Op

  • Veterans RAND 12 (VR-12)

    The Veterans RAND 12 Item Health Survey (VR-12) is a patient-reported global health measure that is used to assess a patient's overall perspective of their health.

    12 Weeks Post Op

  • Veterans RAND 12 (VR-12)

    The Veterans RAND 12 Item Health Survey (VR-12) is a patient-reported global health measure that is used to assess a patient's overall perspective of their health.

    6 Months Post Op

  • Force Patient Engagement

    Engagement on the patient engagement platform including logins, exercise videos watched and patient recorded outcome measures (PROM) compliance during platform access

    Baseline

  • Force Patient Engagement

    Engagement on the patient engagement platform including logins, exercise videos watched and patient recorded outcome measures (PROM) compliance during platform access

    2 Weeks Post Op

  • Force Patient Engagement

    Engagement on the patient engagement platform including logins, exercise videos watched and patient recorded outcome measures (PROM) compliance during platform access

    6 Weeks Post Op

  • Force Patient Engagement

    Engagement on the patient engagement platform including logins, exercise videos watched and patient recorded outcome measures (PROM) compliance during platform access

    12 Weeks Post Op

  • Force Patient Engagement

    Engagement on the patient engagement platform including logins, exercise videos watched and patient recorded outcome measures (PROM) compliance during platform access

    6 Months Post Op

  • Range of Motion via the Knee Glider

    Daily Knee Flexion and Extension for the duration of utilizing the knee glider

    Baseline

  • Range of Motion via the Knee Glider

    Daily Knee Flexion and Extension for the duration of utilizing the knee glider

    2 Weeks Post Op

  • Range of Motion via the Knee Glider

    Daily Knee Flexion and Extension for the duration of utilizing the knee glider

    6 Weeks Post Op

  • Range of Motion via the Knee Glider

    Daily Knee Flexion and Extension for the duration of utilizing the knee glider

    12 Weeks Post Op

  • Range of Motion (Exam / Patient Reported)

    a. Knee Flexion and Extension via in clinic exam or patient reported via the Force Therapeutics Platform

    Baseline

  • Range of Motion (Exam / Patient Reported)

    a. Knee Flexion and Extension via in clinic exam or patient reported via the Force Therapeutics Platform (0 to 110 degrees)

    2 Weeks Post Op

  • Range of Motion (Exam / Patient Reported)

    a. Knee Flexion and Extension via in clinic exam or patient reported via the Force Therapeutics Platform (0 to 110 degrees)

    6 Weeks Post Op

  • Range of Motion (Exam / Patient Reported)

    a. Knee Flexion and Extension via in clinic exam or patient reported via the Force Therapeutics Platform (0 to 110 degrees)

    12 Weeks Post Op

  • Daily NRS Pain (Continuous)

    The NPRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain

    Baseline

  • Daily NRS Pain (Continuous)

    The NPRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain

    2 Weeks

  • Daily NRS Pain (Continuous)

    The NPRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain

    6 Weeks

  • Daily NRS Pain (Continuous)

    The NPRS is a segmented numeric version of the visual analog scale (VAS) in which a respondent selects a whole number (0-10 integers) that best reflects the intensity of his/her pain

    12 Weeks

  • Discharge Services Utilization & Cost

    The Discharge Services Utilization \& Cost survey is intended collect patient discharge information. The survey consists of 16 questions asking about where they went for physical therapy, how much it costs, and if any adverse events resulted in admission to an Emergency Room or Urgent Care.

    6 Weeks Post Op

  • Discharge Services Utilization & Cost

    The Discharge Services Utilization \& Cost survey is intended collect patient discharge information. The survey consists of 16 questions asking about where they went for physical therapy, how much it costs, and if any adverse events resulted in admission to an Emergency Room or Urgent Care.

    12 Weeks Post Op

  • Knee Glider Satisfaction

    The Knee Glider Satisfaction questionnaire is a 4 question survey asking about patient experience using the glider.

    2 Weeks Post Op

  • Knee Glider Satisfaction

    The Knee Glider Satisfaction questionnaire is a 4 question survey asking about patient experience using the glider.

    6 Weeks Post Op

  • Knee Glider Satisfaction

    The Knee Glider Satisfaction questionnaire is a 4 question survey asking about patient experience using the glider.

    12 Weeks Post Op

  • Total Joint Replacement (TJR) Satisfaction

    The TJR Satisfaction survey intends to understand patient experience and satisfaction results with their total joint replacement procedure.

    12 Weeks Post Op

  • Total Joint Replacement (TJR) Satisfaction

    The TJR Satisfaction survey intends to understand patient experience and satisfaction results with their total joint replacement procedure.

    6 Months Post Op

Study Arms (3)

Group C

NO INTERVENTION

Upon consent, patients will be randomized to receive standard of care, and not be given the active range of motion monitor (the knee glider) two weeks prior to surgery. All patients enrolled in the study will have access to Force Therapeutics, patient engagement and outcome collection system utilized by OSI Orthopedic \& Sports Medicine.

Group B

EXPERIMENTAL

Upon consent, patients will be randomized to receive the active range of motion monitor (the knee glider) close to surgery to use postoperatively (through week 4). All patients enrolled in the study will have access to Force Therapeutics, patient engagement and outcome collection system utilized by OSI Orthopedic \& Sports Medicine.

Device: Knee Glider

Group A

EXPERIMENTAL

Upon consent, patients will be randomized to receive the active range of motion monitor (the knee glider) Receives Knee Glider 2 weeks prior to surgery to utilize through postoperative week 4. All patients enrolled in the study will have access to Force Therapeutics, patient engagement and outcome collection system utilized by OSI Orthopedic \& Sports Medicine.

Device: Knee Glider

Interventions

The purpose of this study is to study the efficacy of a remote range of motion monitor, the Knee Glider, alongside a patient engagement platform, Force Therapeutics, on clinical improvements and cost following primary TKA.

Group AGroup B

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals who have undergone Total Knee Arthroplasty (TKA) and have agreed to participate in this study.

You may not qualify if:

  • Individuals who have not undergone TKA.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Alan Cornett, DO

    OSI Orthopedic Sports Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ben Koerner, DO, MBA

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: This study includes 3 arms.
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 14, 2021

First Posted

April 5, 2022

Study Start

April 30, 2022

Primary Completion

December 31, 2022

Study Completion

December 31, 2023

Last Updated

April 14, 2022

Record last verified: 2022-04