The Role of Aquatic-Based Plyometric Exercises for Patients With Juvenile Idiopathic Arthritis

NCT05304832 | Completed

• 1 other identifier: RHPT/0020/0045
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

This study was designed to assess the effect of a 12-week aqua-plyometric (AquaPlyo) training on muscle strength, bone health, and physical ability in children with juvenile idiopathic arthritis (JIA). Forty-eight patients with JIA were randomly allocated to the AquaPlyo group (n = 24, received an aquatic-based plyometric training program, twice/week, over 12 weeks) or the control group (n = 24, received standard exercise program). Both groups were assessed for muscle strength, bone health, and physical ability pre and post-treatment.

Conditions

Juvenile Idiopathic Arthritis

Outcome Measures

Primary Outcomes (4)

• Muscle strength

  Indicated by the peak concentric torque of the quadriceps muscle (Nm). It was measured using an Isokinetic Dynamometer.

  2 months

• Areal bone mineral density

  The amount of bone mineral divided by the bone scanned area (gm/cm2). It was assessed through DEXA scanining.

  2 months

• Volumetric bone mineral density

  The mineral mass per unit volume of bone (gm/cm3). It was assessed through DEXA scanining.

  2 months

• Bone mineral content

  It is the amount of bone mineral in bone tissue (g/cm). It was calculated by summing the bone mineral density values over the projected area.

  2 months

Secondary Outcomes (1)

• Physical ability

  2 months

Study Arms (2)

AquaPlyo group

EXPERIMENTAL

Participants in this group received the AquaPlyo training program

Other: Aqua-Plyometric Exercise

Control group

ACTIVE COMPARATOR

Participants in this group received the standard exercise program.

Other: Standard physical therapy

Interventions

Aqua-Plyometric Exercise OTHER

The aqua-plyometric training was conducted for 45 minutes, twice weekly, for 12 successive weeks. The training was geared toward the lower body and was conducted under close supervision of a licensed pediatric physical therapist in accordance with the safety performance guidelines defined by the American Academy of Pediatrics and the US National Strength and Conditioning Association.

AquaPlyo group

Standard physical therapy OTHER

The program encompassed the standard exercises for patients with JIA (aerobic, weight-bearing, proprioceptive, flexibility, and strengthening exercises). The training was conducted for 40 minutes, two times a week for 12 successive weeks.

Control group

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Confirmed diagnosis of JIA
• Polyarticular onset of JIA with bilateral involvement of the knee joint
• Age between 12 and 18 years
• Stable conditions (i.e., receive stable doses of medications in the past three months)
• Not participating in a regular exercise program in the past six months

You may not qualify if:

• Fixed deformities
• History of joint surgery
• Ankylosing or fractures
• Bone destruction (erosive changes of the knee joint)
• Cardiopulmonary comorbidities
• Recommendation against engaging in potentially explosive physical activities by the attending Rheumatologist.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Ragab K. Elnaggar

Al Kharj, Riyadh Region, Saudi Arabia

Location

Related Publications (1)

• Elnaggar RK, Elfakharany MS. Aqua-Plyometric Exercises-Induced Changes in Muscle Strength, Bone Mineral Properties, and Physical Fitness in Patients With Juvenile Idiopathic Arthritis: A 12-Week, Randomized Controlled Trial. Pediatr Exerc Sci. 2022 Dec 19;35(4):198-205. doi: 10.1123/pes.2022-0044. Print 2023 Nov 1.

  PMID: 36535274 DERIVED

MeSH Terms

Conditions

Arthritis, Juvenile

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Ragab K Elnaggar, PhD

  Prince Sattam Bin Abdulaziz University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: This was a single-blind protocol. The researcher who collected the data was blind to the allocation of treatment
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: A prospective, dual-arm, randomized controlled trial

Study Record Dates

• First Submitted: March 22, 2022
• First Posted: March 31, 2022
• Study Start: December 6, 2020
• Primary Completion: January 30, 2022
• Study Completion: January 30, 2022
• Last Updated: December 28, 2022

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

SA (1)