NCT05304078

Brief Summary

Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers. The TASK III intervention is a unique, comprehensive caregiver intervention program that enables caregivers to develop the necessary skills to manage care for the survivor, while also taking care of their own health.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
332

participants targeted

Target at P75+ for not_applicable

Timeline
9mo left

Started Nov 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Nov 2022Jan 2027

First Submitted

Initial submission to the registry

March 10, 2022

Completed
21 days until next milestone

First Posted

Study publicly available on registry

March 31, 2022

Completed
8 months until next milestone

Study Start

First participant enrolled

November 30, 2022

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2026

Expected
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2027

Last Updated

February 27, 2026

Status Verified

February 1, 2026

Enrollment Period

3.8 years

First QC Date

March 10, 2022

Last Update Submit

February 23, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Life Changes

    Life Changes (i.e., changes in social functioning, subjective well-being, and physical health as a result of providing care) measured by the Bakas Caregiving Outcomes Scale (BCOS). The BCOS consists of 15 items rated on a response scale ranging from -3 (changed for the worst) to +3 (Changed for the best). The items are recoded (-3 = 1) (-2 = 2) (-1 = 3) (0 = 4) (1 = 5) (2 = 6) (3 = 7) so that positive numbers can be obtained for analysis. The recoded responses to the 15 items are summed for a total score with a possible range of 15-105. Higher scores indicate more positive life changes as a result of providing care.

    Baseline to 8 weeks (primary endpoint), long-term baseline to 12, 24, and 52 weeks

Secondary Outcomes (7)

  • Depressive Symptoms

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Other Symptoms

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Unhealthy Days

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Self-management of Steps

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Self-management of Exercise

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • +2 more secondary outcomes

Other Outcomes (6)

  • Mediator: Task Difficulty

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Mediator: Threat Appraisal

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • Mediator: Self-efficacy of Exercise

    Baseline to 8 weeks (shortterm), baseline to 12, 24, and 52 weeks (long-term)

  • +3 more other outcomes

Study Arms (2)

TASK III Group

EXPERIMENTAL

The Telehealth Assessment and Skill-Building Kit (TASK III) group

Behavioral: Telehealth Assessment and Skill-Building Kit (TASK III) Group

ISR Group

ACTIVE COMPARATOR

The Information, Support, and Referral (ISR) group

Behavioral: Information Support and Referral (ISR) Group

Interventions

The ISR group will receive an American Heart Association brochure about family caregiving and 8 weekly calls from a nurse, with a booster call a month later (telephone, videoconferencing, or FaceTime). The ISR nurse will provide information, support, and referral to community resources.

ISR Group

The TASK III group will receive a TASK III Resource Guide (mailed hard copy, USB drive, eBook, and Website access) and 8 weekly calls from a nurse, with a booster call a month later (telephone, videoconferencing, or FaceTime). The TASK III nurse will train caregivers how to assess their needs and concerns, and how to use the TASK III Resource Guide containing content and skill-building tip sheets to address their needs and concerns. Caregivers will also receive an American Heart Association brochure about family caregiving, as well as information, support, and referral to community resources.

TASK III Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Primary caregiver (family member or significant other providing care for a stroke survivor at home).
  • Fluent in the English language (i.e., able to read, speak, and understand English)
  • Access to telephone or computer.
  • No difficulties hearing or talking by telephone or computer.
  • Score 4 or more on a 6-item cognitive impairment screener.
  • Willing to participate in 9 calls from a nurse and 5 data collection interviews (Baseline, 8, 12, 24, 52).

You may not qualify if:

  • Excluded if the survivor:
  • Had not had a stroke.
  • Did not need help from the caregiver.
  • Resides in a nursing home or long-term care facility.
  • Excluded if the caregiver or survivor is:
  • Under the age of 18 years.
  • Prisoner or on house arrest.
  • Pregnant.
  • Terminal illness (e.g., late stage cancer, end-of-life condition, renal failure requiring dialysis).
  • History of Alzheimer's, dementia, or severe mental illness (e.g., suicidal tendencies, schizophrenia, severe untreated depression or manic-depressive disorder).
  • History of hospitalization for alcohol or drug abuse within the past 5 years).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Cincinnati College of Nursing

Cincinnati, Ohio, 45219, United States

Location

Related Publications (1)

  • Bakas T, Miller E, Sucharew H, Kreitzer N, Israel J, Rota M, Harnett B, Dunning K, Jones H, McCarthy M, Brehm B, Austin JK, Mitchell PH. Examining the Efficacy of the Telehealth Assessment and Skill-Building Kit (TASK III) Intervention for Stroke Caregivers: Protocol for a Randomized Controlled Clinical Trial. JMIR Res Protoc. 2025 Mar 25;14:e67219. doi: 10.2196/67219.

    PMID: 39937971BACKGROUND

Related Links

MeSH Terms

Conditions

Stroke

Interventions

Population GroupsReferral and Consultation

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

DemographyPopulation CharacteristicsProfessional PracticeOrganization and AdministrationHealth Services Administration

Study Officials

  • Tamilyn Bakas, PhD, RN

    University of Cincinnati

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor and Jane E. Procter Endowed Chair

Study Record Dates

First Submitted

March 10, 2022

First Posted

March 31, 2022

Study Start

November 30, 2022

Primary Completion (Estimated)

August 31, 2026

Study Completion (Estimated)

January 31, 2027

Last Updated

February 27, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

Qualified investigators may request access to de-identified data from the University of Cincinnati. Special measures will be taken to ensure that caregivers or stroke survivors are not identifiable by any data that are shared. Close collaboration with Dr. Bakas and her research team will be necessary for the use of shared data.

Locations