Comparison of Pulmonary Telerehabilitation and Physical Activity Recommendations in Patients With Post Covid Fibrosis

NCT05299333 | Completed

• 1 other identifier: 2022/25
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Rehabilitation plays a very important role in the management of patients with COVID-19, focusing on respiratory and motor functions, and therefore the importance of establishing treatment strategies to ensure optimal recovery of these patients has been emphasized. It has been stated that physical activity recommendations should be clarified for the management of symptoms associated with prolonged COVID-19 Syndrome and for the continuation of activities of daily living. It has been stated that after COVID-19 pneumonia, it is necessary to evaluate the physical functions of patients with long-term follow-up and to establish rehabilitation programs. The importance of being included in the rehabilitation program was emphasized, especially for patients with lung fibrosis. The primary aim of this study was to compare the effects of pulmonary telerehabilitation and physical activity recommendations on exercise capacity and peripheral muscle strength in patients with pulmonary fibrosis due to COVID-19. The secondary aim of this study is to compare the effects of pulmonary telerehabilitation and physical activity recommendations on symptoms, activity and participation in patients with pulmonary fibrosis due to COVID-19.

Conditions

COVID-19; Pulmonary Fibrosis

Keywords

Post covid fibrosis; Pulmonary Rehabilitation; Physical Activity

Outcome Measures

Primary Outcomes (4)

• Submaximal exercise capacity

  Six minute walk test and

  1 week-8 week

• maximal exercise capacity

  Incremental shuttle walk test

  1 week-8 week

• endurance exercise capacity

  endurance shuttle walk test

  1 week-8 week

• Peripheral muscle strength

  Hand-held dynamometer

  1 week-8 week

Secondary Outcomes (9)

• Physical activity

  1 week-8 week

• Dyspnea

  1 week-8 week

• Fatigue

  1 week-8 week

• Physical fitness

  1 week-8 week

• Functionality

  1 week-8 week

Study Arms (2)

Pulmonary Rehabilitation Group

EXPERIMENTAL

A total of 24 sessions of breathing exercises and high-repetitive muscle endurance and strengthening exercises will be applied to the pulmonary telerehabilitation group for 8 weeks, two days a week and one day a week unsupervised, via online systems. High-repetition muscle endurance and strengthening exercises will be applied to large muscle groups of the lower and upper extremities by creating resistance with body weight and theraband.

Other: Exercise

Physical Activity Group

ACTIVE COMPARATOR

Respiratory exercises and physical activity recommendations will be given to the physical activity group. Physical activity recommendations are; It will include information about the importance of physical activity and walking 3-5 days a week for at least 30 minutes of moderate intensity (4-6 on the Modified Borg scale of perceived exertion level).

Other: Exercise

Interventions

Exercise OTHER

High repetition muscle endurance and strengthening exercises Walking

Physical Activity Group; Pulmonary Rehabilitation Group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \>18 years old
• Patients who have been infected with the COVID-19 virus at least three months ago and have been diagnosed with a positive PCR
• Patients with post-COVID-19 pulmonary fibrosis followed by a pulmonologist
• Patients who have sufficient technological infrastructure to participate in the telerehabilitation program and can adapt to online systems
• Patients who are clinically stable

You may not qualify if:

• Patients with orthopedic/neurological problems that prevent walking and exercise
• Patients with uncontrolled cardiovascular disease
• Patients with uncontrolled medical conditions

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead
• Health Institutes of Turkey: collaborator

Study Sites (1)

Istanbul University-Cerrahpasa

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19; Pulmonary Fibrosis; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Lung Diseases, Interstitial; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: March 25, 2022
• First Posted: March 29, 2022
• Study Start: September 4, 2022
• Primary Completion: March 7, 2025
• Study Completion: March 7, 2025
• Last Updated: April 4, 2025

Record last verified: 2024-02

Locations

TU (1)