Effects of Cognitive-Oriented Intervention on Major Depressive Disorder

NCT05296174 | Completed

• 1 other identifier: TSGH-IRB -1-102-05-019
• Study Type: interventional
• Target: 105
• Locations: 0 countries
• Sites: N/A

Brief Summary

The specific aims of the study were to explore the effects of the cognitive-oriented intervention program for promoting social support on perceived social supports, depression symptoms, and stress-coping strategies for patients with major depressive disorder in Taiwan.

Conditions

Mental Health Issue

Keywords

major depressive disorder; cognitive-oriented intervention

Outcome Measures

Primary Outcomes (3)

• the Chinese Version of the Multidimensional Scale of Perceived Social Support (MSPSS)

  The MSPSS was developed by Zimet, Dahlem, Zimet and Farley (1988). It contains 12 questions, with four questions in each of three categories: (1) support from a significant other (significant other subscale); (2) support from family (family subscale); and (3) support from friends (friend subscale). This study adopts the Chinese version of the social support scale translated by Wang (2008). The higher the scale score meant the higher the perceived level of social support.

  before the intervention to 6 weeks (after the intervention)

• the Coping Orientations to Problems Experienced (COPE) inventory

  The is a four-point scale with a total of 60 questions, including 14 subscales, which include active coping, planning, and suppression of competing activities, restraint, and use of instrumental social support, and humor are tend to problem-focused coping. The higher the score, the more often the response strategy is adopted.

  before the intervention to 6 weeks (after the intervention)

• The Chinese version of the Beck Depression Inventory-II (BDI-II)

  The BDI-II has 21 questions. Higher scores indicated a greater degree of depression.

  before the intervention to 6 weeks (after the intervention)

Study Arms (2)

cognitive-oriented intervention program

EXPERIMENTAL

The intervention group received a 40 mins social support intervention program once a week lasting for 6 weeks. All participants were assessed by questionnaires before and after the intervention.

Other: cognitive-oriented intervention program

received health education program

ACTIVE COMPARATOR

The control group received health education activities with the same frequency as the intervention group. All participants were assessed by questionnaires before and after the intervention.

Other: health education activities program

Interventions

cognitive-oriented intervention program OTHER

The experimental group was offered six 40-minute courses once a week.

cognitive-oriented intervention program

health education activities program OTHER

The control group was offered health education activities once a week.

received health education program

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• diagnosed with MDD by a psychiatrist
• over 20 years of age
• able to speak Mandarin or Taiwanese and able to write.

You may not qualify if:

• patients who were diagnosed with other psychiatric disorders
• with severe cognitive impairment or who could not make conversation acceptably were excluded.

Sponsors & Collaborators

• Mackay Medical College: lead
• National Defense Medical Center, Taiwan: collaborator
• Tri-Service General Hospital: collaborator

MeSH Terms

Conditions

Depressive Disorder, Major

Condition Hierarchy (Ancestors)

Depressive Disorder; Mood Disorders; Mental Disorders

Study Officials

• Shu-Li Cheng, PhD

  Department of Nursing, Mackay Medical College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: The Office of Research and Development

Study Record Dates

• First Submitted: March 16, 2022
• First Posted: March 25, 2022
• Study Start: December 31, 2016
• Primary Completion: July 1, 2018
• Study Completion: July 1, 2018
• Last Updated: June 24, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share