Neuro-Orthopaedic Disorders During Aging in Patients With Neuromotor Disability

NCT05294029 | Recruiting

• 1 other identifier: 2022-002
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

People with neuromotor disability (i.e. following an inborn or acquired spinal cord, cerebral or peripheral neurological lesion) are at risk of worsening their neuro-orthopaedic disorders during aging, including fracture risk. Nevertheless, at the present time, the natural evolution of their neuro-orthopedic disorders and the long-term functional impact of their medical and surgical treatments is unknown. The aim of this study is to describe neuro-orthopedic disorders during aging of patients with neuromotor disability, their functional repercussions, their comorbidities and the therapeutic strategies used.

Conditions

Disability or Chronic Disease Leading to Disablement

Keywords

Neuromotor Disability, Neuro-Orthopaedics

Outcome Measures

Primary Outcomes (1)

• Evolution of mobility during aging

  Walking range

  Through study completion, an average of 1 year

Secondary Outcomes (7)

• Prevalence of falls and fractures

  Through study completion, an average of 1 year

• Characteristics of infiltrative procedures and surgeries

  Through study completion, an average of 1 year

• Changes of devices (orthoses and prostheses) and technical aids used during aging

  Through study completion, an average of 1 year

• Changes of physical activity, as well as barriers and facilitators to physical activity, during aging

  Through study completion, an average of 1 year

• Evolution of comorbidities during aging

  Through study completion, an average of 1 year

Study Arms (1)

All subjects with neuromotor disability

Other: standard of care for patients with neuromotor disability

Interventions

standard of care for patients with neuromotor disability OTHER

clinical examination, radiological, biological and physiological examinations.

All subjects with neuromotor disability

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects with neuromotor disability

You may qualify if:

• Patients \>= 18 years old ;
• Treated in the Neuro Orthopaedic Unit (UPOH) of the Physical Medicine and Rehabilitation Department of our university hospital ;
• Having a neuromotor disability ;
• No opposition to be enrolled in the study from the patient, or from a legally authorized close relative if the patient's state of health does not allow it ;
• Affiliation to a social security scheme.

You may not qualify if:

• Under court protection.

Sponsors & Collaborators

• Institut de Sante Parasport Connecte Synergies: lead
• Assistance Publique - Hôpitaux de Paris: collaborator

Study Sites (1)

Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP

Garches, 92380, France

RECRUITING

MeSH Terms

Interventions

Standard of Care

Intervention Hierarchy (Ancestors)

Quality Indicators, Health Care; Quality of Health Care; Health Services Administration; Health Care Quality, Access, and Evaluation

Study Officials

• François Genêt, MD-PhD

  Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP, 92380 Garches, France

  PRINCIPAL INVESTIGATOR

• Vincent T Carpentier, MD-MSc

  Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP, 92380 Garches, France

  STUDY DIRECTOR

Central Study Contacts

François Genêt, MD-PhD

CONTACT

+33 1 47 10 70 82; francois.genet@aphp.fr

Vincent T Carpentier, MD-MSc

CONTACT

+33 1 47 10 70 82; vincent.carpentier@ispc-synergies.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 5, 2022
• First Posted: March 24, 2022
• Study Start: May 1, 2022
• Primary Completion (Estimated): February 1, 2032
• Study Completion (Estimated): February 1, 2034
• Last Updated: December 23, 2022

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)