NCT05286983

Brief Summary

This prospective single centre longitudinal cohort study enrols preterm infants ≤32+0 weeks of gestation and/or birthweight ≤1500g and their parents. Following a baseline period additional Family Centred Care elements are introduced as potentially better practices, these elements focus on four areas: the NICU (Neonatal Intensive Care Unit) environment, staff training, parental education and psychosocial support to the families. The effect of the implementation of additional Family Centred Care elements on infant, parent and staff outcomes are assessed. The parallel data collection enables to study the interrelation between these three important areas of research.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
495

participants targeted

Target at P75+ for all trials

Timeline
2mo left

Started Oct 2020

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
Oct 2020Jul 2026

Study Start

First participant enrolled

October 1, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

February 23, 2022

Completed
23 days until next milestone

First Posted

Study publicly available on registry

March 18, 2022

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2026

Last Updated

March 30, 2025

Status Verified

March 1, 2025

Enrollment Period

5.8 years

First QC Date

February 23, 2022

Last Update Submit

March 25, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Length of hospital stay

    Length of hospital stay measured by corrected gestational age at discharge

    5.5years

Secondary Outcomes (29)

  • Key neonatal morbidities

    5.5years

  • Weight gain

    5.5years

  • Weight Z-Score

    5.5years

  • Weight

    5.5years

  • Length Z-Score

    5.5years

  • +24 more secondary outcomes

Study Arms (11)

K0 - baseline cohort

45 preterm infants and their parents (average number of patient admissions per 6 months during the last 5 years)

K1 - 1st intervention cohort

All preterm infants and their parents enrolled during the first 6 months period after completion of the baseline cohort and who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K2 - 2nd intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K3 - 3rd intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K4 - 4th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K5 - 5th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K6 - 6th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K7 - 7th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K8 - 8th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K9 - 9th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

K10 - 10th intervention cohort

All preterm infants and their parents enrolled during the 6 months period after the previous 6 months period who are treated according to prespecified Family Centred Care interventions implemented as Potentially Better Practices.

Behavioral: Family Centred Care (FCC) interventions as potentially better practices (PBPs)

Interventions

After the previous period, additional Family Centred Care (FCC) elements will be introduced gradually every 6 months, covering staff training, parent education, psychosocial support for families, and last but not least, the neonatal intensive care unit environment. The focus group consisting of nurses and healthcare professionals will meet regularly and will decide on new FCC interventions as potentially better practices (PBPs). New additional PBPs will be disseminated into the greater team through workshops, hands-on teaching, displays, etc. Potential PBPs for our department enclose: Parent participation on rounds Parent skill self-assessment Parent-to-parent support Regular staff education Improvement of psychosocial support Improvement of neonatal unit surroundings to promote parent-infant-closeness

K1 - 1st intervention cohortK10 - 10th intervention cohortK2 - 2nd intervention cohortK3 - 3rd intervention cohortK4 - 4th intervention cohortK5 - 5th intervention cohortK6 - 6th intervention cohortK7 - 7th intervention cohortK8 - 8th intervention cohortK9 - 9th intervention cohort

Eligibility Criteria

Age1 Minute - 14 Days
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

The study population consists of inborn and outborn preterm infants of ≤32+0 weeks of gestational age (GA) and/or birthweight ≤1500g who are admitted to the Level 3 NICU and their parents

You may qualify if:

  • ≤32+0 weeks of gestational age (GA) and/or birthweight ≤1500g
  • biparental (or guardian) written informed consent

You may not qualify if:

  • severe congenital anomalies (e.g. cyanotic heart disease, severe lung hypoplasia, congenital diaphragmatic hernia)
  • decision not to provide full life support
  • decision for palliative care before study entry
  • parents with severe psychiatric disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Mihatsch Walter

Ulm, Baden-Wurttemberg, 89231, Germany

ACTIVE NOT RECRUITING

Department of General Pediatrics and Neonatology, Justus- Liebig- University, Feulgenstrasse 12, D-35392 Giessen, Germany

Giessen, Hesse, 35390, Germany

RECRUITING

Related Publications (2)

  • Schuler R, Ehrhardt H, Mihatsch WA. Safety and Parental Satisfaction With Early Discharge of Preterm Infants on Nasogastric Tube Feeding and Outpatient Clinic Follow-Up. Front Pediatr. 2020 Aug 25;8:505. doi: 10.3389/fped.2020.00505. eCollection 2020.

    PMID: 32984217BACKGROUND
  • Schuler R, Woitschitzky L, Eiben C, Beck J, Jagers A, Windhorst A, Kampschulte B, Petzinger J, Waitz M, Kilsdonk MOR, Neubauer BA, Zimmer KP, Ehrhardt H, Brosig B, Mihatsch WA. Multidimensional assessment of infant, parent and staff outcomes during a family centered care enhancement project in a tertiary neonatal intensive care unit: study protocol of a longitudinal cohort study. BMC Pediatr. 2023 Jul 7;23(1):344. doi: 10.1186/s12887-023-04165-0.

MeSH Terms

Interventions

Methods

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

  • Rahel Schuler

    Department of General Pediatrics and Neonatology, Justus- Liebig- University, Giessen, Germany

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Consultant Neonatology

Study Record Dates

First Submitted

February 23, 2022

First Posted

March 18, 2022

Study Start

October 1, 2020

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

July 1, 2026

Last Updated

March 30, 2025

Record last verified: 2025-03

Locations