Feasibility@48: Cross Sectional Study of Intensive Care Unit Mobility Practices Across the United Kingdom

NCT05281705 | Unknown

• 1 other identifier: EDGE:125652 IRAS:262426
• Study Type: observational
• Target: 750
• Locations: 1 country
• Sites: 1

Brief Summary

Intensive Care Unit (ICU) patients commonly experience muscle loss at a rate of 2-3% day. Traditionally, critically ill patients have been managed in bed, however current research suggests that prolonged bedrest cause mechanical silencing of the muscles and exacerbates this muscle wasting. This ICU acquired weakness (ICUAW) leads to poor functional outcome and higher mortality. Research suggests that early out-of-bed mobilisation should occur within 48-hours of ICU admission to militate against this risk, however, this is only achieved in 30% of cases. Common barriers to mobilisation are unstable blood pressure, ventilation, sedation and fatigue. It is plausible that 48-hours is an unrealistic timeframe for mobilisation. The aim of this study is to explore the mobility practices on a given day in UK adult ICUs. The objectives are to:

1. 1.Determine the level of mobility that is achieved by each patient on adult ICUs, on a given day in the UK.
2. 2.Determine the typical physiological profile of patients on ICU that are both able and unable to participate in antigravity exercise
3. 3.Determine the proportion of adult ICU admissions that achieve out of bed mobilisation in the first 48-72 hours
4. 4.Explore clinician decision making about mobilisation

Conditions

Critical Illness; Rehabilitation

Keywords

Physiotherapy; Rehabilitation; Mobilisation

Outcome Measures

Primary Outcomes (1)

• The proportion of patients achieving a ICU mobility scale more than 3 on the day of the study

  Day 1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patient in level 2 \& 3 ICU beds in the UK

You may qualify if:

• All patients who are admitted to a participating ICU on the study day will be included

You may not qualify if:

• None

Sponsors & Collaborators

• University College, London: lead
• University College London Hospitals: collaborator

Study Sites (1)

University College London Hospitals NHS Trust

London, United Kingdom

Location

Related Publications (1)

• Black C, Sanger H, Battle C, Eden A, Corner E. Feasibility of mobilisation in ICU: a multi-centre point prevalence study of mobility practices in the UK. Crit Care. 2023 Jun 1;27(1):217. doi: 10.1186/s13054-023-04508-4.

  PMID: 37264471 DERIVED

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2022
• First Posted: March 16, 2022
• Study Start: March 3, 2022
• Primary Completion: March 3, 2022
• Study Completion: March 30, 2023
• Last Updated: March 31, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)