Exercise With Dual Task in Knee Osteoarthritis

NCT05280080 | Completed

• 1 other identifier: OA-22-02
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate the neuromuscular and perceptual responses, pain intensity and performance in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with a self-regulated mathematical dual-task.

Conditions

Knee Osteoarthritis

Keywords

Knee Osteoarthritis; Electromyography; Muscle Activity; Resistance Training

Outcome Measures

Primary Outcomes (4)

• Self-reported pain intensity (Visual Analogue Scale (VAS) Scale 0-10)

  Change from baseline to the end of the session, and the change between the dual-task and the regular condition.

  Pre exercise, immediate post session, and 10 minutes after session.

• Pressure pain thresholds

  Change from baseline to the end of the session, and the change between the dual-task and the regular condition.

  Pre exercise, immediate post session, and 10 minutes after session.

• HDsEMG

  Change from baseline to the end of the session, and the change between the dual-task and the regular condition.

  During each experimental session and during each exercise condition.

• Performance

  Maximum number of exercise repetitions performed.

  During each experimental session and during each exercise condition.

Secondary Outcomes (6)

• Tampa Scale of Kinesiophobia (TSK 11)

  Pre session.

• Pain Catastrophizing Scale (PCS)

  Pre session.

• Chronic Pain Self-Efficacy Scale (CPSS)

  Pre session.

• WOMAC questionaire for patients with hip or knee osteoarthritis.

  Pre session.

• Heart Rate

  Pre exercise, immediate post session, and 10 minutes after session.

Study Arms (2)

Regular Task

ACTIVE COMPARATOR

Knee extensions.

Other: Resistance exercise

Dual Task

EXPERIMENTAL

Knee extensions while also doing a self-regulated mathematical dual-task.

Other: Resistance exercise

Interventions

Resistance exercise OTHER

Do the maximum number of repetitions of externally-resisted (50% 1RM) knee extensions.

Dual Task; Regular Task

Eligibility Criteria

• Age: 55 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• men and women above 55 years old.
• diagnosed with severe knee osteoarthritis.
• scheduled for unilateral TKA surgery in a local hospital during 2021- 2022.

You may not qualify if:

• pain in the contralateral limb (maximum pain, ≥80 of 100 mm on a VAS during daily activities).
• another hip or knee joint replacement in the previous year.
• any medical condition in which exercise was contraindicated.
• participated in exercise programs (\>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study.
• history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of dual tasks.

Sponsors & Collaborators

• University of Valencia: lead

Study Sites (1)

Clinic Universitary Hospital of Valencia

Valencia, 46010, Spain

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• José Casaña

  University of Valencia

  PRINCIPAL INVESTIGATOR

• Joaquín Calatayud

  University of Valencia

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of the Physiotherapy Department

Study Record Dates

• First Submitted: February 15, 2022
• First Posted: March 15, 2022
• Study Start: March 21, 2022
• Primary Completion: May 13, 2022
• Study Completion: May 20, 2022
• Last Updated: May 24, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)