The Immune Response to Stroke
1 other identifier
observational
40
1 country
1
Brief Summary
Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2021
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 24, 2021
CompletedFirst Submitted
Initial submission to the registry
March 3, 2022
CompletedFirst Posted
Study publicly available on registry
March 14, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 6, 2029
ExpectedMarch 14, 2022
March 1, 2022
4.5 years
March 3, 2022
March 3, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
The B cell and T cell response in peripheral blood
1 day (subject inclusion)
Study Arms (1)
Stroke patients
Interventions
Analysis of immune responses in peripheral blood
Eligibility Criteria
Patients suffering from acute cerebral infarction
You may qualify if:
- Stroke \< 72 h
- Age \> 18 years
You may not qualify if:
- Brain hemorrhage verified by CT or MRI scan
- Previous or present immunological disease or other serious comorbidity
- Ongoing immune respons after infection or vaccination \< 1 month
- Cognitive without ability to understand and/or give an informed consent to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Akershus University Hospital
Lørenskog, Norway
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
March 3, 2022
First Posted
March 14, 2022
Study Start
June 24, 2021
Primary Completion
December 31, 2025
Study Completion (Estimated)
June 6, 2029
Last Updated
March 14, 2022
Record last verified: 2022-03
Data Sharing
- IPD Sharing
- Will not share