NCT04034680

Brief Summary

Continuity of care in home care services is necessary to facilitate the assessment and treatment of persons with dementia and cognitive failure. TIME (Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms) is a multi-component intervention with a biopsychosocial approach, based on the theoretical framework of cognitive behavioral therapy and person-centred care. The trial is designed to assess the effects of TIME on Neuropsychiatric symptoms for persons (NPS) with dementia in home care services.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2019

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 24, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 26, 2019

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2020

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2020

Completed
Last Updated

September 29, 2020

Status Verified

September 1, 2020

Enrollment Period

1.4 years

First QC Date

July 24, 2019

Last Update Submit

September 28, 2020

Conditions

Keywords

Behavioral symptomsDementiaNevropsychiatric symptomsPsychological symptomsThe TIME model

Outcome Measures

Primary Outcomes (1)

  • Affective symptoms measured by the Cornell Scale for Depression in Dementia (CSDD)

    The change from baseline of affective symptoms as defined in the Cornell Scale for Depression in Dementia (CSDD), a scale ranging from 0-38 where a higher score indicates more severe depressive symptoms.

    6 months

Secondary Outcomes (7)

  • Neuropsychiatric Inventory - nursing home version (NPI-NH): Sub syndrome anxiety and depression

    6 months

  • NPI-NH: all separate items

    6 months

  • NPI-NH: caregiver distress score

    6 months

  • Quality of life measured by the scale QUALID

    6 months

  • Change in Relatives Stress scale Score (RSS)

    6 months

  • +2 more secondary outcomes

Study Arms (2)

Home care services - Intervention group

EXPERIMENTAL

Totally 5 municipalities (25 persons with dementia) will be included in the intervention group, and will receive training in the TIME model. This includes two hours of lectures about dementia and neuropsychiatric symptoms (NPS) and three hours of training and roleplay in using the TIME model. The staff of the home care service will receive the TIME manual and access to the TIME website with access to additional educational and information files. From each municipality, three staff members, called TIME administrators, will receive additional three hours of lectures and roleplay in TIME, and will thereafter have the responsibility for performing the intervention.

Other: TIME

Home care services - Control group

ACTIVE COMPARATOR

Totally 5 municipalities (25 persons with dementia) will be included in the Control group. The municipalities in the control group will receive the same two hours lectures about dementia and NPS as the intervention group. After the cluster RCT pilot study is ended, municipalities in the control group will receive the same three-hour lessons in the TIME as the intervention group of municipalities.

Other: Education-only intervention

Interventions

TIMEOTHER

The intervention of the TIME model includes two hours of lectures about dementia and NPS and three hours of training and roleplay in using TIME. The staff of the home care service will receive the TIME manual and access to the TIME website with access to additional educational materials. From each municipality, three staff members called TIME administrators, will receive additional three hours of lectures and roleplay in TIME, and will thereafter have the responsibility for performing the intervention.

Home care services - Intervention group

Staff in the home care service in municipalities in the control group will receive thesame two hours lectures about dementia and NPS as the intervention grorp. After the cluster RCT pilot study is ended, municipalities in the control group will receive the same three-hour lessons in the TIME as the intervention group of municipalities.

Home care services - Control group

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Dementia, defined as a score of 1 or more on the Clinical Dementia Rating Scale (CDR)
  • A minimum of 15 minutes of home care services per day for the last 4 weeks
  • NPS, defined as a score on the NPI-NH affective subsyndrom (NPI depression + NPI anxiety) of 12 or more
  • Informed consent from the participant or family or next-of-kin

You may not qualify if:

  • Terminal disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Research centre for Age-related Functional decline and Disease (AFS) at Innlandet Hospital Trust

Ottestad, 2312, Norway

Location

MeSH Terms

Conditions

DementiaBehavioral Symptoms

Interventions

Time

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersBehavior

Intervention Hierarchy (Ancestors)

Physical Phenomena

Study Officials

  • Sverre Bergh, PhD

    The Research centre for Age-related Functional decline and Disease (AFS)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Participants will be masked for the study arm they are randomised to. Staff in the home care service are aware of the study arm their patients are in, while assessors that will interview home care staff by telephone are masked for study randomisation.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Cluster randomized trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 24, 2019

First Posted

July 26, 2019

Study Start

February 1, 2019

Primary Completion

June 15, 2020

Study Completion

June 30, 2020

Last Updated

September 29, 2020

Record last verified: 2020-09

Locations