Diffusion-tensor Imaging in Brain Tumors Evaluation
Contribution of Diffusion Tensor Imaging and Tractography in Primary and Secondary Brain Tumors Evaluation
1 other identifier
observational
100
1 country
1
Brief Summary
Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization. In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 15, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 14, 2021
CompletedFirst Submitted
Initial submission to the registry
February 20, 2022
CompletedFirst Posted
Study publicly available on registry
March 2, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
March 14, 2022
CompletedMarch 2, 2022
February 1, 2022
27 days
February 20, 2022
February 20, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Tract damage
Assess the damage of tracts at baseline preoperative
3 months
Secondary Outcomes (1)
Craniotomy size
3 months
Study Arms (2)
Patients with primary brain tumors
Patients with secondary brain tumors
Interventions
In this study patients with suspected primary and secondary brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation.
Eligibility Criteria
Patients with suspected primary or secondary brain tumors, confirmed by routine MRI evaluation followed by surgical treatment and histopathological exam.
You may qualify if:
- brain tumors confirmed by routine MRI evaluation
- surgical treatment with histopathological diagnosis
You may not qualify if:
- MRI contraindications
- past or present neurological or neurosurgical condition, beside the tumor
- pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
SCJU Mures
Târgu Mureş, Mureș County, 540136, Romania
Study Officials
- PRINCIPAL INVESTIGATOR
Mihail Porutiu
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Phd student
Study Record Dates
First Submitted
February 20, 2022
First Posted
March 2, 2022
Study Start
February 15, 2021
Primary Completion
March 14, 2021
Study Completion
March 14, 2022
Last Updated
March 2, 2022
Record last verified: 2022-02