NCT05255497

Brief Summary

This study examined the effects of balance exercises performed with the Biodex Balance System (BBS) on nerve conduction, sensory symptoms, and muscle strength in patients with diabetes-related neuropathy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
27

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 2, 2017

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 10, 2019

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 20, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

February 16, 2022

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 24, 2022

Completed
Last Updated

March 11, 2022

Status Verified

February 1, 2022

Enrollment Period

1.8 years

First QC Date

February 16, 2022

Last Update Submit

February 24, 2022

Conditions

Outcome Measures

Primary Outcomes (3)

  • The effect of biodex balance training on muscle strength was evaluated.

    Muscle test was evaluated with a manual dynamometer. The measurements of both groups before and after the training were compared.

    Change from baseline to 8 weeks

  • The effect of biodex balance training on protective senses

    Protective senses was assessed with monofilament and 128 Hz tuning fork

    Change from baseline to 8 weeks

  • The effect of biodex balance training on motor nerves

    Nerve conduction test was assessed with electromyograph

    Change from baseline to 8 weeks

Study Arms (2)

Biodex Balance Group

EXPERIMENTAL

This group performed exercises using the biodex balance system

Device: Biodex Balance Exercise System

Control Group

NO INTERVENTION

This group was informed about diabetes self-management.

Interventions

Patients in the intervention group (n=14) performed exercises using the computerized BBS. The control group (n=13) was just informed about diabetes self-management.

Biodex Balance Group

Eligibility Criteria

Age45 Years - 76 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diabetes-related neuropathy based on laboratory tests, clinical findings, and nerve conduction study

You may not qualify if:

  • increased risk of non-diabetes related neuropathy: history of autoimmune, cerebrovascular, or chronic infectious disease, cancer, chemotherapy and/or radiotherapy, radicular neuropathy, chronic kidney and liver failure, alcoholism or other substance abuse, and mental or physical disabilities (including blindness). We also excluded patients who didn't speak Turkish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dokuz Eylul University

Izmir, Balcova/Incialtı, 35340, Turkey (Türkiye)

Location

Related Publications (1)

  • Reyhanioglu DA, Yildirim G, Sengun IS, Kara B. Effects of Computer-based Balance Exercises on Balance, Pain, Clinical Presentation and Nerve Function in Patients With Diabetic Peripheral Neuropathy: A Randomized Controlled Study. J Musculoskelet Neuronal Interact. 2024 Jun 1;24(2):168-177.

MeSH Terms

Conditions

Diabetic NeuropathiesDiabetes Mellitus

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System DiseasesDiabetes ComplicationsEndocrine System DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Gaye Yıldırım, Dr

    Dokuz Eylul University

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 16, 2022

First Posted

February 24, 2022

Study Start

September 2, 2017

Primary Completion

June 10, 2019

Study Completion

September 20, 2020

Last Updated

March 11, 2022

Record last verified: 2022-02

Locations