NCT05249504

Brief Summary

In their day to day, persons do from simple to more or less complicated tasks and activities (ie: stand from a chair, open a door, shopping, read, drive, play chess, remind an appointment...). Such ability to do things is called capacity. Intrinsic capacity is the combination of all the physical and mental capacities that a person has, and reach its maximum in the early adulthood and then declines as the person ages. Each kind of capacity declines at her own speed (which may be faster or slower according to each person lifestyle), and once drops below a threshold may lead to a reduction in quality of life and loss of autonomy. Nevertheless there are some actions that may be effective to prevent or slow such decline. To do so the investigators have design an intervention that combines several things of different nature (what is know as a complex intervention) called AMICOPE. The AMICOPE intervention is performed in the community or in primary care centers through 12 weekly group sessions of 2 h 30 min which combine structured and adapted physical activity, group dynamics to promote social support and address loneliness, social isolation and depressive symptoms, and dietary advice. Our study is addressed to persons over 70 with light problems in mobility, nutrition or mood state. The purpose of this study is to assess if the AMICOPE intervention is better than the standard advice to follow healthy lifestyles to improve or maintain self-perceived health, mobility, nutritional status an psychological wellbeing.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
212

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2022

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 15, 2021

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 21, 2022

Completed
1 month until next milestone

Study Start

First participant enrolled

April 1, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2023

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2024

Completed
Last Updated

February 21, 2022

Status Verified

February 1, 2022

Enrollment Period

1.2 years

First QC Date

December 15, 2021

Last Update Submit

February 10, 2022

Conditions

Keywords

FrailtyIntrinsic capacityMulticomponent interventionRandomized clinical TrialQuality of life

Outcome Measures

Primary Outcomes (1)

  • Self-perceived health

    Change in self-perceived health status according to the Euroqol Visual Analogue Scale, where participants scores from 0 (worse state) to 100 (better state) their current perceived health

    Baseline, after the intervention (average 16 weeks)

Secondary Outcomes (8)

  • Functional status

    Baseline, after the intervention (average 16 weeks)

  • Nutritional status

    Baseline, after the intervention (average 16 weeks)

  • Depressive symptoms

    Baseline, after the intervention (average 16 weeks)

  • Autonomy in daily life.

    Baseline, after the intervention (average 16 weeks)

  • Health related quality of life.

    Baseline, after the intervention (average 16 weeks)

  • +3 more secondary outcomes

Study Arms (2)

1. Intervention group

EXPERIMENTAL

AMICOPE multicomponent intervention: * Physical activity (VIVIFRAIL program): 10 hours. * Nutrition: 6,5 hours. * Psychology: 6,5 hours. * Personal autonomy: 4,5 hours * Learn about community resources: 2, 5 hours

Other: VIVIFRAILOther: NutritionBehavioral: PsychologyBehavioral: Personal autonomyOther: Community resources

2. Control group

ACTIVE COMPARATOR

Control group participants will receive usual advice on healthy lifestyle habits and a follow-up phone call from healthcare professionals.

Other: Standard recommendations

Interventions

VIVIFRAIL is a set of physical activity programs (designed according to several elderly functional level profiles) aimed to prevent motor disability and improve quality of life. It works endurance, flexibility, balance and strength. https://web.archive.org/web/20210907041944/https://vivifrail.com/

1. Intervention group

Sessions to learn about personal nutrition habits, offer nutritional advice, and acquire skills to incorporate simple healthy nutrition guidelines into everyday life. A visit to a supermarket to make it easier to read and understand the basic information on nutrition labels.

1. Intervention group
PsychologyBEHAVIORAL

Relaxation techniques to manage mood, a photo-elicitation dynamic to address loneliness, and a dynamic to collectively develop a map of health assets in the neighborhood or territory to obtain information on community resources. Finally, a group visit is planned to a community facility previously agreed upon by the participants.

1. Intervention group

Review practical cases on personal autonomy, the proper use of medications, and discover basic cognitive stimulation strategies.

1. Intervention group

Learn about community resources

1. Intervention group

Usual advice provided at primary care office accompanied to booklets about healthy lifestyles

2. Control group

Eligibility Criteria

Age70 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • To live in the community
  • To be able to move autonomously to the intervention place
  • To Have a deficit in at least one mobility, vitality or psychological domains in the Integrated Care for Older People (ICOPE) screening tool confirmed by a reference test, namely:
  • A - Mobility: unable to stand up from a chair 5 times in less than 14 seconds AND having less than 10 points in the Short Physical Performance Battery (SPPB).
  • B - Vitality: any nutritional problem from the ICOPE screening tool (loss of appetite OR losing more than 3 Kg not intentionally in the last 3 months) AND having less than 12 points in MNA (malnutrition or malnutrition risc).
  • C - Psychological: any depressive symptoms from the ICOPE screening tool (answer that in the last two weeks has had feelings of sadness, melancholy OR hopelessness or refer lack of interest or pleasure when doing things) AND the presence of at least two or more symptoms on the 5-item Geriatric Depression Scale (GDS5).

You may not qualify if:

  • People with previous diagnosis of dementia or cognitive decline with a score below 24 points in the Minimental State Examination (MMSE).
  • People in the end of life.
  • People who have factors that prevent or contraindicate the performance of the planned interventions, such as contraindication to physical activity, mental or (non-corrected) communication issues that makes it difficult to participate in group dynamics.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

DepressionCognitive DysfunctionHearing LossVision DisordersFrailty

Interventions

Nutritional StatusPsychologyPersonal AutonomyCommunity Resources

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorCognition DisordersNeurocognitive DisordersMental DisordersHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsEye DiseasesPathologic Processes

Intervention Hierarchy (Ancestors)

Nutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological PhenomenaHealth StatusDemographyPopulation CharacteristicsBehavioral SciencesBehavioral Disciplines and ActivitiesFreedomHuman RightsSocial Control, FormalHealth Care Economics and OrganizationsPrinciple-Based EthicsEthicsHealth Care Quality, Access, and Evaluation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Open and Pragmatic Parallel Randomized Controlled Clinical Trial
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 15, 2021

First Posted

February 21, 2022

Study Start

April 1, 2022

Primary Completion

June 30, 2023

Study Completion

August 31, 2024

Last Updated

February 21, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will share

The sponsor only will share data from participants that have provided written consent to share its anonymized data for studies with scientific purposes related with well-being, quality of life and autonomy of the elderly persons. Once the database is closed all identifying data collected to develop the study (ie: names and contact phones to make appointments) will be removed from the database. Any date variable will be replaced by a time reference variable, taking as reference the day of the first visit (ie: instead of date of birth and date of visit, will be replaced by the age). Other actions may be performed to ensure a reasonable balance between the data loss and the risk of re-identification, as editing quasi-identificatory variables (ie categorizing/aggregating participant data, as creating age groups) or removed (ie removing the data identifying the centers) or removing cases with a high degree of singularity given the quasi-identificatory variables combination.

Time Frame
The data can be requested 18 months after publishing the results.
Access Criteria
Upon request by non-profit organizations. The purpose of the request must match the purpose for which the participants have given their sharing consent. Requester must cite and recognize the source of the data in their works, as far as the funds that the project has received.