Muscle Analyze In Patient With Disc Herniation

NCT05245214 | Completed

• 1 other identifier: 06-2021/30
• Study Type: observational
• Target: 330
• Locations: 1 country
• Sites: 1

Brief Summary

This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation. In this study, the effects of disc herniation, herniation severity, age, and spinal biomechanics were investigated.

Conditions

Disk Herniated Lumbar

Outcome Measures

Primary Outcomes (1)

• Muscle cross-area

  The cross-sectional area of the Multifidus, Erector Spina, Quadratus Lumborum, and Psoas Major muscles on both sides were measured using the T2-weighted axial Magnetig Resonance Imaging.

  1 Month

Secondary Outcomes (1)

• Lumbar Biomechanic

  1 Month

Study Arms (2)

Patients with disc herniation

Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Diagnostic Test: Magnetic Resonance Imaging

Patient in control group

Patients without disc herniation, severe disc degeneration and spondylolisthesis were included in the control group.

Diagnostic Test: Magnetic Resonance Imaging

Interventions

Magnetic Resonance Imaging DIAGNOSTIC_TEST

Muscle analysis by Magnetic Resonance Imaging

Patient in control group; Patients with disc herniation

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients without disc herniation, severe disc degeneration and spondylolisthesis were also withdrawn from the System and included in the control group. 80 individuals with aged between 20-70 years included control group.

You may qualify if:

• Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

You may not qualify if:

• Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Sponsors & Collaborators

• Karamanoğlu Mehmetbey University: lead

Study Sites (1)

Karamanoğlu Mehmetbey University

Karaman, Turkey (Türkiye)

Location

Related Publications (1)

• Sun D, Liu P, Cheng J, Ma Z, Liu J, Qin T. Correlation between intervertebral disc degeneration, paraspinal muscle atrophy, and lumbar facet joints degeneration in patients with lumbar disc herniation. BMC Musculoskelet Disord. 2017 Apr 20;18(1):167. doi: 10.1186/s12891-017-1522-4.

  PMID: 28427393 BACKGROUND

MeSH Terms

Interventions

Magnetic Resonance Imaging

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Ayşenur Gökşen, PhD

  Karamanoğlu Mehmetbey University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Prof

Study Record Dates

• First Submitted: January 10, 2022
• First Posted: February 17, 2022
• Study Start: March 2, 2021
• Primary Completion: January 1, 2022
• Study Completion: January 7, 2022
• Last Updated: March 10, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)