NCT05227573

Brief Summary

Hypoxia and reduced oxygen partial pressure is commonly occurring after abdominal surgery. This study aims to investigate whether similar changes also occur after orthopedic surgery in the form of upper limb surgery. Inclusion: 60 patients undergoing orthopedic surgery in the form o knee-, hip-, shoulder- or elbow surgery. Exclusion: Dementia or cognitive impairment that makes it impossible to participate in studies. Arterial blood gas and lung function are undertaken before surgery, the day after surgery and at follow-up.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Feb 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 24, 2022

Completed
14 days until next milestone

First Posted

Study publicly available on registry

February 7, 2022

Completed
2 days until next milestone

Study Start

First participant enrolled

February 9, 2022

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2024

Completed
Last Updated

February 13, 2023

Status Verified

February 1, 2023

Enrollment Period

2.2 years

First QC Date

January 24, 2022

Last Update Submit

February 10, 2023

Conditions

Postoperative ComplicationsOrthopedic Disorder

Outcome Measures

Primary Outcomes (1)

  • Oxygen partial pressure

    Change in oxygen partial pressure after surgery

    1 day

Secondary Outcomes (7)

  • Vital capacity

    1 day

  • Oxygen partial pressure

    1 month

  • Carbon dioxide partial pressure

    1 day

  • Carbon dioxide partial pressure

    1 month

  • Vital capacity

    1 month

  • +2 more secondary outcomes

Interventions

Orthopedic surgeryPROCEDURE

Knee-, hip-, shoulder- and elbow surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients undergoing shoulder or elbow surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept of Surgery, University hospital

Umeå, Västerbotten County, 90185, Sweden

RECRUITING

MeSH Terms

Conditions

Postoperative ComplicationsMusculoskeletal Diseases

Interventions

Orthopedic Procedures

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

TherapeuticsSurgical Procedures, Operative

Study Officials

  • Karl A Franklin, Prof

    Surgical and Perioperative Sciences, Surgery, Umeå University, Sweden

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Karl A Franklin, Prof

CONTACT

+46 706884745karl.franklin@umu.se

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Profesor, Consultant surgeon

Study Record Dates

First Submitted

January 24, 2022

First Posted

February 7, 2022

Study Start

February 9, 2022

Primary Completion

May 1, 2024

Study Completion

May 1, 2024

Last Updated

February 13, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share

Locations

SE(1)