Characteristics and Clinical Outcomes of Peritoneal Dialysis Patients

NCT05224466 | Unknown

• 1 other identifier: PD
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

Peritoneal dialysis patients worldwide account for about 11% of the global dialysis population. The global annual growth rate of peritoneal dialysis is estimated to be 8%, which is listed as the preferred method of renal replacement therapy in most countries. Although peritoneal dialysis has been widely used, due to complications such as peritoneal dialysis related infection, peritoneal ultrafiltration failure and EPS, the failure rate of peritoneal dialysis technology is high, and the 3-year technical survival rate is only 64%. Therefore, this study intends to explore clinical strategies for maintaining the long-term peritoneal dialysis by analyzing the clinical characteristics of patients , as well as the differences of risk factors affecting the survival rate of peritoneal dialysis technology at different time stages of peritoneal dialysis treatment.

Conditions

Peritoneal Dialysis Complication

Outcome Measures

Primary Outcomes (1)

• baseline clinical characteristics before PD

  clinical characteristics about age,sex,comorbidities before PD,laboratory data would be aggregated from the existing record to find out the differences between the long-term PD patients and the others that may affect their clinical outcome.

  within one month before the start of PD

Secondary Outcomes (1)

• the factors that may lead to the termination of PD

  up to 20 years

Study Arms (3)

A

defined as patients survived on PD for more than 10 years

B

defined as patients survived on PD for 5-10 years

C

defined as patients survived on PD within 5 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

ESRD patients who start the PD at the first time

You may qualify if:

• ESRD patients
• The first time of peritoneal dialysis

You may not qualify if:

• Age \<18 years at start of PD
• Transfer or follow-up loss
• Previous transplantation or HD history
• Incomplete clinical data

Sponsors & Collaborators

• Shanghai Jiao Tong University School of Medicine: lead

Study Sites (1)

Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, 200001, China

Location

Study Officials

• Wei Fang, MD

  RenJi Hospital

  STUDY DIRECTOR

Central Study Contacts

Na Jiang, MD

CONTACT

+86-21-53882014; Jiangjiang198311@163.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Chief Physician of Nephrology

Study Record Dates

• First Submitted: December 14, 2021
• First Posted: February 4, 2022
• Study Start: March 1, 2022
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2024
• Last Updated: February 4, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)