NCT05223985

Brief Summary

The objective of this multicentre study is to collect preoperative, intra operative, early, short, intermediate and mid-term(one years) on the related clinical complications and functional outcomes of market-approved Alcis products to demonstrate safety and performance of these devices in a real-world setting.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
74

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2022

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 23, 2021

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 4, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

April 29, 2022

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2024

Completed
Last Updated

August 5, 2024

Status Verified

August 1, 2024

Enrollment Period

2.7 years

First QC Date

December 23, 2021

Last Update Submit

August 2, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Signal quality

    percentage of contacts that measured a signal

    through study completion, an average of 10 days".

  • Modification of Electroencephalography trace post-coagulation

    Modification of Electroencephalography trace post-coagulation

    through study completion, an average of 1 hours".

Interventions

SEEG and thermocoagulation

Eligibility Criteria

Age18 Months - 65 Years
Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The patient treated by Depth Coagulation Electrode is drug-resistant epilepsies patient.

You may qualify if:

  • To be included, patients must be:
  • months to 65 years
  • Patient with drug-resistant and disabling focal epilepsy
  • Informed and willing to sign an informed consent form approved by EC / For minors: if one of the parents cannot consent within the timeframe provided by the protocol, then only one parent's signature is required
  • Affiliation to the social security or foreign regime recognized in France
  • Must have undergone an SEEG exploration with one ALCIS device before the date of the initiation visit
  • Follow-up visits (at least 12-month) must be prospective
  • Must have complete information available for each completed visit (demographics, preoperative information, implantation information, device details) \*.

You may not qualify if:

  • Not able to comply with the study procedures based on the judgment of the assessor (e.g. cannot comprehend study questions, inability to keep scheduled assessment times)
  • Any medical condition that could impact the study at investigator's discretion (e.g. allergy…)
  • Pregnant women (contraindication to SEEG exploration)
  • Adult subject to legal protection measure
  • Skull thickness inferior at 2 mm

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Centre d'Investigation Clinique : Equipe Timone Adultes CPCET

Marseille, 13354, France

RECRUITING

Pôle Investigation - Fondation Adolphe de Rothschild

Paris, Île-de-France Region, 75019, France

RECRUITING

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 23, 2021

First Posted

February 4, 2022

Study Start

April 29, 2022

Primary Completion

December 30, 2024

Study Completion

December 30, 2024

Last Updated

August 5, 2024

Record last verified: 2024-08

Locations