Regional Blocks for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery

NCT05218746 | Unknown DMC

• 1 other identifier: Regional blocks in VATS
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to compare serratus anterior plane block and erector spinae plane block for postoperative analgesia after VATS as measured by the duration till 1st requirement of analgesia.

Conditions

Pain, Postoperative

Outcome Measures

Primary Outcomes (1)

• the duration till 1st requirement of analgesia

  The time from the end of the operation till Visual analogue score more than 3

  postoperative first day

Secondary Outcomes (1)

• Analgesic consumption

  postoperative first day

Study Arms (2)

Serratus anterior block

EXPERIMENTAL

Regional analgesic block of anterolateral chest wall

Procedure: Serratus anterior plane block

Erector spinae block

EXPERIMENTAL

Regional analgesic block for the whole chest wall

Procedure: Erector spinae block

Interventions

Serratus anterior plane block PROCEDURE

High-frequency linear transducer will be placed on the patient's midaxillary line in the transverse plane, at the level of the fifth rib, with the indicator oriented toward the operator's left. With the rib, pleural line, and overlying serratus anterior and latissimus dorsi muscles visualized, Then, using ultrasound guidance, the needle will be advanced in-plane at an angle of approximately 45 degrees towards the fifth rib . one millileter normal saline will be injected to confirm placement and to hydro-dissect the fascial layers and open the potential space.

Serratus anterior block

Erector spinae block PROCEDURE

A high-frequency linear ultrasound probe will be placed in a longitudinal orientation 3 cm from the midline. Once the erector spinae muscle and the transverse processes is identified, spinal needle will be inserted in a caudad-to-cephalad direction until the tip lay in the interfacial plane deep to the erector spinae muscle.

Erector spinae block

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with American Society of Anesthesiologists (ASA) physical status 1-3 --
• scheduled for VATS .

You may not qualify if:

• ≤20 or ≥80 years old.
• Refusing to participate in the study .
• History of allergy to the medications used in the study.
• Contraindication to regional anesthesia (including coagulopathy and local infection).
• Severe hepatic impairement (serum protein \< 3g/dl and serum bilirubin \> 3mg/dl) .
• Renal dysfunction (as determined by creatinine levels greater than 2mg/dl or predicted creatinine clearance (CLcr)\<50ml/min).
• Psychiatric disorder.
• Pregnancy.
• Body mass index (BMI) ≥40 or ≤18 kg/m2.

Sponsors & Collaborators

• Ain Shams University: lead

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: January 31, 2022
• First Posted: February 1, 2022
• Study Start: February 1, 2022
• Primary Completion: August 1, 2022
• Study Completion: September 1, 2022
• Last Updated: February 28, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share