NCT05217875

Brief Summary

Dysfunctional breathing might participate to dyspnoea in long COVID-19. This study investigate the prognosis of patients diagnosed with dysfunctional breathing after SARS-CoV-2 infection in our center.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2021

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 31, 2022

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 1, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2022

Completed
Last Updated

February 1, 2022

Status Verified

December 1, 2021

Enrollment Period

7 months

First QC Date

January 31, 2022

Last Update Submit

January 31, 2022

Conditions

COVID-19Dysfunctional Breathing

Keywords

COVID-19Dysfunctional breathingHyperventilation syndromeSighserratic breathing

Outcome Measures

Primary Outcomes (1)

  • Persistence/resolution of dysfunctional breathing at follow-up visit

    defined by persistence/resolution of dyspnea, as compared with patient's baseline (equivalent level of dyspnea as before COVID-19).

    6 to 9 monts from diagnosis

Secondary Outcomes (9)

  • Change in ventilatory patterns (tidal volume [VT], breathing frequency [BF] at isowork as compared with baseline

    6 to 9 monts from diagnosis

  • Dispersion of VT and BF during the CPET

    6 to 9 monts from diagnosis

  • Change in ETCO2 and PaCO2

    6 to 9 monts from diagnosis

  • Qualitative changes (increase/decrease/no change of DB pattern of CPET)

    6 to 9 monts from diagnosis

  • Score HADS changes

    6 to 9 monts from diagnosis

  • +4 more secondary outcomes

Eligibility Criteria

Age14 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

\- Patients of 14 years or more diagnosed with DB after COVID-19 using a combined approach of symptoms and CPET in the Hospitals of Sion, of Martigny or Rennaz

You may qualify if:

  • patients 14 years or more
  • diagnosis of DB after SARS-CoV-2 at our long covid clinic using a combined approach of symptoms and CPET analysis in the hospitals of Sion, Martigny or Rennaz

You may not qualify if:

  • Refusal to participate
  • comorbidities preventing the CPET or PFT to be carried out

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre hospitalier du valais romand

Martigny-Ville, Switzerland

RECRUITING

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Pierre-Olivier v Bridevaux

CONTACT

+41792079069pierre-olivier.bridevaux@hopitalvs.ch

Léon Genecand

CONTACT

+41799372687leon.genecand@hcuge.ch

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 31, 2022

First Posted

February 1, 2022

Study Start

November 1, 2021

Primary Completion

June 1, 2022

Study Completion

August 1, 2022

Last Updated

February 1, 2022

Record last verified: 2021-12

Locations

CH(1)