Effect of Selected Types of Breathing Exercises on Different Outcome Measures in Covid-19 Patients

NCT05753293 | Completed

• 1 other identifier: P.T.REC/012/004298
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Coronavirus disease 2019 (COVID-19) infection leads to significant respiratory that have negative impact on function and quality of life (QoL). Breathing exercises are effective and important in patients with COVID-19.

Conditions

COVID-19

Outcome Measures

Primary Outcomes (5)

• Modified Borg Scale to Measure dyspnea:

  is a 0 to 10 rated numerical score used to measure dyspnea as reported by the patient with higher score indicates breathing problem.

  week

• Blood Samples:

  The blood samples will be collected before starting and at the end of the study to measure levels of CRP, d-dimer and CBC to test.

  week

• The Six-minute walk test:

  The six-minute walk test (6MWT) will be done pre \& post exercise program.

  week

• Pittsburgh Sleep Quality Index (PSQI)

  The PSQI questionnaire was used to measure sleep quality using an 18-item scale containing seven items that included sleep quality, sleep duration, sleep latency, habitual sleep efficiency, sleep disturbance, use of sleeping medications, and daytime dysfunction. Each dimension scored between 0-3, with a total score ranging from 0-21, and a higher score indicating lower sleep quality

  week

• The 36-Item Short-Form Health Survey (SF-36) Questionnaire

  The SF-36 is a 36-item scale, which measures eight domains of health status: physical functioning (10 items); physical role limitations (four items); bodily pain (two items); general health perceptions (five items); energy/vitality (four items); social functioning (two items); emotional role limitations (three items) and mental health (five items) the scores are weighted sums of the questions in each section. Scores range from 0 - 100 Lower scores = more disability, higher scores = less disability

  week

Study Arms (2)

Bhastrika pranayama

EXPERIMENTAL

done in sitting posture and the following instructions: The back must be kept straight and shoulder muscles should be kept relaxed, patient was asked to close the right nostril with right thumb and to bring right elbow to the level of right shoulder. To close the eyes, inhale and exhale through left nostril-first slowly, then a little faster, The subject was asked to do the above steps about 20-25 times, (Then the subject was asked to take a long breath in and retain it for as long as possible, This is one cycle of Bhastrika pranayama. The subject has to repeat this cycle by closing left nostril and breathing through right nostril.

Other: breathing exercise

Buteyko breathing exercise

EXPERIMENTAL

Step 1 beginning control pause (CP) the patient inhales and then exhales through the nose and then holds their breath until the point they feel either the first clear and distinct desire to breath or involuntary movement or jerk coming from diaphragm.Step 2 three to five minutes of relaxed reduced-volume breathing or slow breathing the patient gradually reduced their breathing until they feel a light lack of air. they sustain these while staying relaxed. Step 3 maximum pause (MP) the maximum pause begins with gentel inhalation and exhalation. Then the breath is held as long as possible but not to the point of severe discomfort. Step 2 and step 3 are then repeated up to 5 times. Final control pause: same as step 1.

Other: breathing exercise

Interventions

breathing exercise OTHER

Buteyko breathing technique developed to control hyperventilation and anxiety which leads to shortness of breath. It uses series of exercises to teach patients to breathe less deeply and less rapidly /Bhastrika "Bellow Breathing" is diaphragmatic breathing - deep breathing involving the diaphragm rather than the accessory muscles. Regulated pranayama exercises require inhalation, maintaining isometric contraction of respiratory muscles and forceful expiration. These techniques will strengthen respiratory muscles

Also known as: Bhastrika pranayama . Buteyko breathing exercise

Bhastrika pranayama; Buteyko breathing exercise

Eligibility Criteria

• Age: 40 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Their age ranged from 40 to 50years old.
• with confirmed COVID-19 by positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan).
• Moderate hospitalized covid-19 patient.
• full consciousness and oriented.
• BMI 20-25 kg/m2.

You may not qualify if:

• presence of any type of musculoskeletal disorder prohibits the patient from participating in the study
• history of chronic diseases as (diabetes, hypertension and heart diseases)
• Any type of obvious clinically mental or cognitive impairment.
• History of previous other respiratory disease.

Sponsors & Collaborators

• Basma Mosaad Abd-elrahman Abushady: lead

Study Sites (1)

Faculty of Physical Therapy Cairo University

Giza, 11595, Egypt

Location

MeSH Terms

Conditions

COVID-19

Interventions

Breathing Exercises

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Master student at Department of Physical Therapy for Cardiovascular, Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University

Model Details: Sixty patients of both genders with age range from 40-50 years old will be recruited from El Khankah Centeral Hospital with positive nasopharyngeal swab samples and presence of ground-glass opacification in their chest computed tomography scan (CT-scan) will be assigned randomly into two groups A \& B and take their medications.

Study Record Dates

• First Submitted: February 24, 2023
• First Posted: March 3, 2023
• Study Start: May 1, 2022
• Primary Completion: July 22, 2022
• Study Completion: September 25, 2022
• Last Updated: March 3, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)