Direct Peritoneal Resuscitation for Intra-abdominal Catastrophes

NCT05208489 | Unknown

• 1 other identifier: 14677
• Study Type: observational
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

It is a retrospective study. Patients, who presented with either traumatic or general surgery emergencies, undergone exploratory laparotomy, had an open abdomen management and received Direct Peritoneal Resuscitation in addition to standard resuscitation will be considered as meeting the criteria to collect the data.

Conditions

Intestinal Perforation; Intestinal Obstruction; Trauma Abdomen

Outcome Measures

Primary Outcomes (1)

• Post operative outcomes

  intra abdominal infections and other complications

  through out the hospitalization and 30 days after discharge.

Secondary Outcomes (1)

• length of hospital stay

  post procedure to 30 days after discharge.

Interventions

there is no intervention involved in this study OTHER

there is no intervention involved in this study.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult patients 18 and above, who presents with either traumatic or general surgery emergencies and undergone exploratory laparotomy had an open abdomen management and received DPR in addition to standard resuscitation will be considered as meeting the criteria to be in the study.

You may qualify if:

• Adult patients 18 years of age or older.
• Trauma or General surgery patients who undergo emergency abdominal surgery via laparotomy and who had open abdominal management during the index procedure at our institution.
• Patients who are transferred to our institution with an already open abdomen will also be eligible if they required continued open abdominal management.

You may not qualify if:

• Patients \<18 years are excluded.

Sponsors & Collaborators

• New York Medical College: lead

Study Sites (1)

New York Medical College

Valhalla, New York, 10595, United States

RECRUITING

Related Publications (3)

• Smith JW, Garrison RN, Matheson PJ, Franklin GA, Harbrecht BG, Richardson JD. Direct peritoneal resuscitation accelerates primary abdominal wall closure after damage control surgery. J Am Coll Surg. 2010 May;210(5):658-64, 664-7. doi: 10.1016/j.jamcollsurg.2010.01.014.

  PMID: 20421025 BACKGROUND

• Zakaria el R, Hurt RT, Matheson PJ, Garrison RN. A novel method of peritoneal resuscitation improves organ perfusion after hemorrhagic shock. Am J Surg. 2003 Nov;186(5):443-8. doi: 10.1016/j.amjsurg.2003.07.006.

  PMID: 14599604 RESULT

• Crafts TD, Hunsberger EB, Jensen AR, Rescorla FJ, Yoder MC, Markel TA. Direct peritoneal resuscitation improves survival and decreases inflammation after intestinal ischemia and reperfusion injury. J Surg Res. 2015 Dec;199(2):428-34. doi: 10.1016/j.jss.2015.06.031. Epub 2015 Jun 18.

  PMID: 26169030 RESULT

MeSH Terms

Conditions

Intestinal Perforation; Intestinal Obstruction; Abdominal Injuries

Condition Hierarchy (Ancestors)

Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Wounds and Injuries

Study Officials

• Kartik Prabhakaran, MD

  New York Medical College

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Anuritha Tirumani, MBBS

CONTACT

914-493-3470; anuritha.tirumani@wmchealth.org

Abbas Smiley, MD

CONTACT

914-493-3470; abbas.smiley@wmchealth.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Trauma Medical Director

Study Record Dates

• First Submitted: December 28, 2021
• First Posted: January 26, 2022
• Study Start: December 16, 2021
• Primary Completion: June 30, 2022
• Study Completion: June 1, 2023
• Last Updated: January 26, 2022

Record last verified: 2022-01

Locations

US (1)