Pulmonary Hypertension in Patients Attending Sohag University Hospital: A Focus on The Etiology

NCT05207683 | Unknown

• 1 other identifier: Soh-Med-21-12-20
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Assessment of pulmonary hypertension in patients attending Sohag university hospital ( in out patient clinic or in patient) focusing on the etiology of pulmonary hypertension

Conditions

Patients With Pulmonary Hypertension

Outcome Measures

Primary Outcomes (1)

• Detection of the causes of pulmonary hypertension in patients attending Sohag university hospital

  We will diagnose the cause of pulmonary hypertension in each participant. This will be done by following the diagnostic algorithm of European Society of Cardiology/ European Respiratory Society (ESC/ERS) 2015 guidelines (e.g. we will exclude that pulmonary hypertension is secondary to pulmonary disease by performing adequate assessment of the patient medical history and clinical examination, performing chest x-ray and or high resolution CT chest, spirometry...), so we will know the pattern of pulmonary hypertension etiology in patients attending of Sohag university hospital

  one year

Study Arms (1)

patients with pulmonary hypertension

patients who are more than 18 years old , diagnosed with pulmonary hypertension by echocardiography

Other: echocardiography

Interventions

echocardiography OTHER

All the patients will be subjected to thorough medical history and clinical examination and the results of the previous investigations will be collected aiming for reaching the diagnosis of the etiology of pulmonary hypertension. ct pulmonary angiography and then right heart catheterization will be done in case of undiagnosed etiology.

Also known as: electrocardiogram, chest X ray, high resolution Ct chest, spirometry, arterial blood gases, abdominal ultrasound, CT pulmonary angiography, serological tests e.g Anti nuclear antibodies, anti double stranded DNA antibodies..., right heart catheterization

patients with pulmonary hypertension

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

pulmonary hypertension patients attending Sohag university hospital (either admitted in the hospital or attending the out patient clinics)

You may qualify if:

• patients who are 18 years old or more
• patients with pulmonary hypertension diagnosed with echocardiography

You may not qualify if:

• patient who are less than 18 years old

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

• Prins KW, Thenappan T. World Health Organization Group I Pulmonary Hypertension: Epidemiology and Pathophysiology. Cardiol Clin. 2016 Aug;34(3):363-74. doi: 10.1016/j.ccl.2016.04.001.

  PMID: 27443134 BACKGROUND

• Galie N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Respir J. 2015 Oct;46(4):903-75. doi: 10.1183/13993003.01032-2015. Epub 2015 Aug 29.

  PMID: 26318161 BACKGROUND

• Simonneau G, Montani D, Celermajer DS, Denton CP, Gatzoulis MA, Krowka M, Williams PG, Souza R. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respir J. 2019 Jan 24;53(1):1801913. doi: 10.1183/13993003.01913-2018. Print 2019 Jan.

  PMID: 30545968 BACKGROUND

MeSH Terms

Interventions

X-Rays; Blood Gas Analysis

Intervention Hierarchy (Ancestors)

Electromagnetic Radiation; Electromagnetic Phenomena; Magnetic Phenomena; Physical Phenomena; Radiation; Radiation, Ionizing; Blood Chemical Analysis; Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Investigative Techniques

Central Study Contacts

esraa a saad, assistant lecturer

CONTACT

01065567768; esraa.abdo@med.sohag.edu.eg

kamal a ata, professor

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant lecturer of chest diseases and tuberculosis sohag university hospitals

Study Record Dates

• First Submitted: December 29, 2021
• First Posted: January 26, 2022
• Study Start: October 1, 2021
• Primary Completion: September 1, 2022
• Study Completion: September 1, 2022
• Last Updated: January 26, 2022

Record last verified: 2022-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)