NCT05206253

Brief Summary

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
115

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2022

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 11, 2022

Completed
14 days until next milestone

First Posted

Study publicly available on registry

January 25, 2022

Completed
4 months until next milestone

Study Start

First participant enrolled

May 30, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

May 29, 2024

Status Verified

May 1, 2024

Enrollment Period

1.3 years

First QC Date

January 11, 2022

Last Update Submit

May 24, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in lean tissue mass

    Lean tissue mass measured by DXA

    12 weeks

Secondary Outcomes (9)

  • Change in fat mass

    12 weeks

  • Change in biceps muscle thickness

    12 weeks

  • Change in triceps muscle thickness

    12 weeks

  • Change in quadriceps muscle thickness

    12 weeks

  • Change in hamstrings muscle thickness

    12 weeks

  • +4 more secondary outcomes

Study Arms (3)

Whole egg powder

EXPERIMENTAL

Dietary supplementation with whole egg powder after resistance training sessions

Dietary Supplement: Whole egg powder

Whey protein powder

ACTIVE COMPARATOR

Dietary supplementation with whey protein powder after resistance training sessions

Dietary Supplement: Whey protein powder

Maltodextrin placebo

PLACEBO COMPARATOR

Dietary supplementation with maltodextrin placebo after resistance training sessions

Dietary Supplement: Maltodextrin placebo

Interventions

Whole egg powderDIETARY_SUPPLEMENT

Nutritional supplementation during a 12 week resistance training program

Whole egg powder
Whey protein powderDIETARY_SUPPLEMENT

Nutritional supplementation during a 12 week resistance training program

Whey protein powder
Maltodextrin placeboDIETARY_SUPPLEMENT

Nutritional supplementation during a 12 week resistance training program

Maltodextrin placebo

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Resistance training experience for at least one year

You may not qualify if:

  • Having taken any nutritional supplements the past 30 days
  • Currently using anabolic steroids
  • Currently taking corticosteroids
  • Allergies to dairy or egg products
  • Identifying any medical conditions as determined by the "Get Active Questionnaire"

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Regina

Regina, Saskatchewan, S4S 0A2, Canada

Location

University of Saskatchewan

Saskatoon, Saskatchewan, S7N5B2, Canada

Location

MeSH Terms

Conditions

Muscular Atrophy

Condition Hierarchy (Ancestors)

Neuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Study Officials

  • Philip Chilibeck, Ph.D.

    University of Saskatchewan

    PRINCIPAL INVESTIGATOR
  • Darren Candow, Ph.D.

    University of Regina

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 11, 2022

First Posted

January 25, 2022

Study Start

May 30, 2022

Primary Completion

August 31, 2023

Study Completion

August 31, 2023

Last Updated

May 29, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations