Musical Training Programme to Improve Neurocognitive Functioning of Children Surviving Brain Tumours

NCT05202925 | Completed DMC

• 1 other identifier: HKCH-REC-2021-008
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

We aim to conduct a feasibility study to determine the feasibility and suitability of implementing a musical training program for children surviving brain tumours. This study will demonstrate the feasibility of implementing a musical training program in improving the neurocognitive functioning of surviving brain tumours.

Conditions

Cancer Childhood; Brain Tumor

Outcome Measures

Primary Outcomes (3)

• Recruitment rate of the study

  the proportion of subjects who are eligible and invited and consent to participate.

  at baseline before the start of the intervention

• Response rate of the study

  The proportion of subjects who complete the questionnaires and assessments at baseline and 12 months after starting the intervention

  at baseline and 12 months after starting the intervention

• Retention rate of the study

  The proportion of subjects who complete the whole intervention from baseline to 12 months.

  at baseline and 12 months after starting the intervention

Secondary Outcomes (4)

• Nonverbal intelligence scores of the subject

  at baseline and 12 months after starting the intervention

• Attention scores of the subject

  at baseline and 12 months after starting the intervention

• Processing speed scores of the subject

  at baseline and 12 months after starting the intervention

• Executive functions scores of the subject

  at baseline and 12 months after starting the intervention

Study Arms (1)

Musical Training

EXPERIMENTAL

All subjects in the intervention group will receive a weekly 45-minute lesson, one-to-one musical training for 52 weeks.

Other: Musical Training Program

Interventions

Musical Training Program OTHER

a weekly 45-minute lesson, one-to-one musical training

Musical Training

Eligibility Criteria

• Age: 7 Years - 16 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• children who have completed cancer treatment at least 2 months previously;
• aged between 7 and 16 years,
• able to speak Cantonese and read Chinese, and
• those who have not undertaken any musical training following their cancer diagnosis.

You may not qualify if:

• \. those survivors with evidence of cancer recurrence or second malignancy in their medical records

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead
• Health and Medical Research Fund: collaborator

Study Sites (1)

The Hong Kong Children's Hospital

Hong Kong, Hong Kong

Location

Related Publications (1)

• Chung JOK, Li WHC, Leung YD, Cheung TCK, Chiu SY, Pong MSY, Chan GCF. The feasibility, acceptability, and potential efficacy of a musical training program in promoting neuroplasticity among survivors of pediatric brain tumors: A cohort study. Eur J Oncol Nurs. 2025 Jun;76:102851. doi: 10.1016/j.ejon.2025.102851. Epub 2025 Feb 28.

  PMID: 40043524 DERIVED

MeSH Terms

Conditions

Neoplasms; Brain Neoplasms

Condition Hierarchy (Ancestors)

Central Nervous System Neoplasms; Nervous System Neoplasms; Neoplasms by Site; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Joyce Chung

  The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor, School of Nursing

Study Record Dates

• First Submitted: January 10, 2022
• First Posted: January 24, 2022
• Study Start: October 1, 2021
• Primary Completion: January 1, 2023
• Study Completion: February 15, 2024
• Last Updated: July 30, 2024

Record last verified: 2024-07

Locations

HK (1)