NCT05196243|Unknown
Multimodal Imaging Based on Pathological and Genomic Characteristics
A New Multimodal Imaging Technique Based on Pathological and Genomic Characteristics of Gastrointestinal Mucosa
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A New Multimodal Imaging Technique Based on Pathological and Genomic Characteristics of Gastrointestinal Mucosa
Sponsor study identifier
observational
200
1 country
1
Study Start
March 21, 2022
Actual (reported)Primary Completion
June 1, 2022
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
July 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Mitochondrial DNA mutations in normal gastric tissue, early gastric cancer and advanced gastric cancer were identified by single cell sequencing, and the origin of gastric stem cells was traced and new molecular markers were found. At the same time, organize industry-university-research-medical inspection joint research, aiming at the advanced layout of new structural and functional imaging technologies, combined with some new imaging technologies, such as holography, fluorescence, etc., to explore and develop a new composite endoscopic imaging technology that is advanced, original and suitable for China's national conditions, in order to develop a prototype of multimodal structural and functional imaging digestive endoscope without contrast agent.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 5, 2022
Actual (reported)January 19, 2022
Actual (reported)March 21, 2022
Actual (reported)June 1, 2022
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
July 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Single cell sequencing and identification of mitochondrial DNA variation in gastrointestinal lesions
Single cell sequencing and identification of mitochondrial DNA mutations in gastrointestinal lesions were carried out to trace the clonal origin of cells and look for molecular markers
1 month
To explore the multimodal imaging technique for the diagnosis of gastrointestinal mucosal lesions
The tissue characteristics are analyzed by the full spectrum imaging device, the location, distribution and aggregation of key molecules on the cell membrane are observed by the high resolution imaging device, the imaging probe with high labeling efficiency and biosafety is developed, and the clinical application is discussed. in order to realize the information fusion of structural and functional imaging in the process of gastrointestinal tumor evolution and diagnosis and treatment.
1 month
Study on the genomic and molecular pathological characteristics of gastrointestinal mucosal lesions
Study on the genomic and molecular pathological characteristics of normal gastrointestinal mucosa
Patients diagnosed as gastritis, gastric cancer, intestinal polyps and colorectal cancer
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
People diagnosed or suspected of one of the following common digestive mucosal diseases: gastritis, gastric cancer, colorectal polyps, colorectal cancer
The First Medical Center of Chinese PLA General Hospital
Beijing, Beijing Municipality, 100853, China
Mucosal tissues or cells of gastritis, gastric cancer, intestinal polyps and colorectal cancer obtained by endoscopic biopsy or resection
Yan Liu, MD
Beijing 302 Hospital
First Submitted
January 5, 2022
First Posted
January 19, 2022
Study Start
March 21, 2022
Actual (reported)Primary Completion
June 1, 2022
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Hyper-Spectral Endoscopy for Detection of Early Neoplasia in Barrett's Oesophagus
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Study Completion
July 1, 2024
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
April 1, 2022
Record last verified: 2022-03
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Source: ClinicalTrials.gov.
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