The Impact of Late Effects After Treatment for Bladder Cancer on Quality of Life

NCT05195515 | Enrolling By Invitation DMC

• 1 other identifier: CONQUER
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 5

Brief Summary

Bladder Cancer prognosis, treatment, and subsequent morbidity and mortality vary between the different stages, thus resulting in a different impact on patients' lives. There are some well known late effects of the treatments for bladder cancer, but the knowledge of their impact on patients Quality of Life is sparse. This study aims to determine the prevalence of late effects impact on Quality of Life and potential risk factors for impairment.

Conditions

Bladder Cancer

Keywords

Quality of Life; Bladder Cancer; Late effects

Outcome Measures

Primary Outcomes (1)

• Health-related Quality of Life

  Changes in Quality of Life measured using validated instruments

  5 years from baseline inclusion

Secondary Outcomes (1)

• Prevalence of late effects

  5 years from baseline inclusion

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients over 18 years of age, referred due to hematuria

You may qualify if:

• Patients are eligible if they are referred to a hospital in the Central Region Denmark, due to hematuria between 01/01/2022 and 01/01/2023
• Ability to understand written and oral Danish

You may not qualify if:

• Known Alzheimers disease
• Diagnosed other causes explaining the hematuria

Sponsors & Collaborators

• Aarhus University Hospital: lead
• University of Aarhus: collaborator
• National Research Center for Survivorship and Late Adverse Effects Following Pelvic Organ Cancer, Denmark: collaborator

Study Sites (5)

Department of Urology, Aarhus University Hospital

Aarhus N, 8200, Denmark

Location

Department of Urology, Regional Hospital Gødstrup

Gødstrup, 7400, Denmark

Location

Department of Urology, Regional Hospital Horsens

Horsens, 8700, Denmark

Location

Department of Urology, Regional Hospital Randers

Randers, 8900, Denmark

Location

Department of Urology, Regional Hospital Viborg

Viborg, 8800, Denmark

Location

MeSH Terms

Conditions

Urinary Bladder Neoplasms

Condition Hierarchy (Ancestors)

Urologic Neoplasms; Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Urinary Bladder Diseases; Urologic Diseases; Male Urogenital Diseases

Study Officials

• Jørgen Bjerggaard Jensen, Professor

  Department of Urology, Aarhus University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, DMSc

Study Record Dates

• First Submitted: January 7, 2022
• First Posted: January 19, 2022
• Study Start: January 1, 2022
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: March 3, 2026

Record last verified: 2026-03

Locations

DK (5)