NCT05193500

Brief Summary

The goal of this research is to explore abilities to learn word meanings from overheard speech in children with ASD (and, as a control, typically developing children). Specific Aim 3 (Experiment 3): Determine whether children with ASD can learn verbs and pronouns by overhearing. Most prior work on learning from overheard speech has focused on learning nouns that label objects. This experiment extends this work to study other kinds of words.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
179

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2022

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 3, 2022

Completed
15 days until next milestone

First Posted

Study publicly available on registry

January 18, 2022

Completed
7 months until next milestone

Study Start

First participant enrolled

August 1, 2022

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 5, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 5, 2025

Completed
3 months until next milestone

Results Posted

Study results publicly available

March 30, 2025

Completed
Last Updated

March 30, 2025

Status Verified

November 1, 2024

Enrollment Period

2.4 years

First QC Date

January 3, 2022

Results QC Date

January 6, 2025

Last Update Submit

March 17, 2025

Conditions

Outcome Measures

Primary Outcomes (2)

  • Object Preference for Verbs

    Proportion of Time During Which Children's Eye Gaze is Directed Toward the Target Object in the Window from 1.0-2.5 Seconds after the Test Question

    During test phase of the experimental session (within 3 seconds after the learning phase); 1.0-2.5 seconds after the test question

  • Object Selection for Pronouns

    Proportion of trials on which children select the correct object that matches the pronoun

    During test phase of the experimental session (within approx. 5 seconds of being asked the test question)

Study Arms (2)

Verbs

EXPERIMENTAL

Children hear a novel verb in an experimental context that is personally relevant to them (e.g., addressed, of interest) or neutral.

Behavioral: Verbs

Pronouns

EXPERIMENTAL

Children hear a pronoun in an experimental context that is personally relevant to them (e.g., addressed, of interest) or neutral.

Behavioral: Pronouns

Interventions

VerbsBEHAVIORAL

New verbs are introduced that are personally relevant to the child or neutral.

Verbs
PronounsBEHAVIORAL

Pronouns are used that directly refer to the child or are neutral.

Pronouns

Eligibility Criteria

Age24 Months - 71 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • \* children with or without a diagnosis of ASD between 24 to 71 months of age

You may not qualify if:

  • native language is not English
  • born premature (\< 36 weeks)
  • has uncorrected hearing or vision impairments
  • has developmental disorders or medical conditions other than ASD that affect language or cognition (excepting psychiatric conditions often comorbid with ASD such as ADHD)
  • has a history of photosensitive epileptic seizures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Emerson College

Boston, Massachusetts, 02116, United States

Location

New York University

New York, New York, 10012, United States

Location

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders

Results Point of Contact

Title
Dr. Sudha Arunachalam
Organization
New York University

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 3, 2022

First Posted

January 18, 2022

Study Start

August 1, 2022

Primary Completion

January 5, 2025

Study Completion

January 5, 2025

Last Updated

March 30, 2025

Results First Posted

March 30, 2025

Record last verified: 2024-11

Locations