Influence of Trauma on Pain Area and Widespreadness in Chronic Pain Patients

NCT05190367 | Completed

• 1 other identifier: 9681
• Study Type: observational
• Target: 914
• Locations: 1 country
• Sites: 1

Brief Summary

It is well known that patients suffering from chronic pain report higher levels of pain, anxiety, and depression if they have experienced a traumatic event. However, little is know about pain area and widespreadness. In this retrospective study, we want to investigate whether pain area and widespreadness differs in chronic pain patients with and without traumatic events. To test this hypothesis we will retrospectively analyse pain drawings collected at the pain outpatient department from Hannover Medical School. Participants will be divided into four groups depending on the severity of their traumatic events: no trauma; accidental trauma; interpersonal trauma; post-traumatic stress disorder (PTSD).

Conditions

Chronic Pain; Trauma

Outcome Measures

Primary Outcomes (2)

• Difference in pain area

  Pain area derived from electronic pain drawings (SymptomMapper). The score ranges from 0 to 100% body area.

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

• Difference in pain widespreadness

  Widespread pain index (WPI) derived from electronic pain drawings (SymptomMapper). The score ranges from 0 (no pain) to 19 (pain affects all possible regions).

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

Secondary Outcomes (10)

• Difference in current pain

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

• Difference in mean pain in the last four weeks

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

• Difference in maximal pain in the last four weeks

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

• Difference in acceptable pain

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

• Difference in sleep impairment

  First visit of each patient at the Pain outpatient department of Hannover Medical School between 2019-02-28 and 2020-07-07

Study Arms (4)

No trauma

Patients suffering from chronic pain without traumatic life events

Accidental trauma

Patients suffering from chronic pain who have experienced at least one accidental trauma

Interpersonal trauma

Patients suffering from chronic pain who have experienced at least one interpersonal trauma

PTSD

Patients suffering from chronic pain and diagnosed with PTSD

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with chronic pain visiting the pain outpatient department at Hannover Medical School.

You may qualify if:

• Chronic pain

You may not qualify if:

• None

Sponsors & Collaborators

• Hannover Medical School: lead

Study Sites (1)

Hannover Medical School

Hanover, 30625, Germany

Location

Related Publications (1)

• Manuel J, Rudolph L, Beissner F, Neubert TA, Dusch M, Karst M. Traumatic Events, Posttraumatic Stress Disorder, and Central Sensitization in Chronic Pain Patients of a German University Outpatient Pain Clinic. Psychosom Med. 2023 May 1;85(4):351-357. doi: 10.1097/PSY.0000000000001181. Epub 2023 Feb 21.

  PMID: 36825929 DERIVED

MeSH Terms

Conditions

Chronic Pain; Wounds and Injuries

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Jorge Manuel Sánchez

  Hannover Medical School

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 10, 2021
• First Posted: January 13, 2022
• Study Start: February 28, 2019
• Primary Completion: July 7, 2020
• Study Completion: July 7, 2020
• Last Updated: January 13, 2022

Record last verified: 2022-01

Locations

DE (1)