Determinant of Repeat Revascularization After Percutaneous Coronary Intervention

NCT05189249 | Completed DMC

• 1 other identifier: 5004-CHS-ERC-17
• Study Type: observational
• Target: 270
• Locations: 1 country
• Sites: 1

Brief Summary

To determine factors associated with repeat revascularization among adults aged 25 years and above within 5 years of first Percutaneous Coronary Intervention (PCI) at a tertiary care hospital.

Conditions

Percutaneous Coronary Intervention; Coronary Artery Disease

Keywords

Repeat revascularization; Percutaneous Coronary Intervention; Coronary Artery Disease

Outcome Measures

Primary Outcomes (1)

• Factors associated with repeat revascularization

  Identify factors that are associated with repeat coronary intervention in the form of PCI or CABG once patient has been discharged after index PCI and during follow-up years (excluding staged PCI planned within three weeks of index PCI).

  January 2018 to December 2018

Study Arms (2)

Case

Patients who have undergone repeat revascularization within 5 years of undergoing index PCI at Aga Khan University Hospital Karachi.

Other: No intervention performed

Control

Patients who have not undergone repeat revascularization within 5 years of undergoing index PCI at Aga Khan University Hospital Karachi.

Other: No intervention performed

Interventions

No intervention performed OTHER

No intervention performed. Participants were enrolled retrospectively and medical records were accessed for data.

Case; Control

Eligibility Criteria

• Age: 25 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The target population includes all the adult patients age 25 years and above who were revascularized at least at the Aga Khan University Hospital, Karachi.

You may qualify if:

• Aged 25 years and older
• Undergone repeat revascularization within 5 years of undergoing index PCI (from 2011 to 2017).

You may not qualify if:

• If suffering from any hypercoagulable disorder
• Revascularization procedure was per-formed outside the study setting
• Staged PCI within 3 weeks or planned PCI within 6 months of Index PCI.
• Patients aged 25 years and older
• Undergone PCI once from the year 2011 to 2017.
• If suffering from any hypercoagulable disorder.

Sponsors & Collaborators

• Aga Khan University: lead

Study Sites (1)

Aga Khan University

Karachi, Sindh, 74800, Pakistan

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Komal Valliani, BScN, MScEB

  Aga Khan University Karachi

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 28, 2021
• First Posted: January 12, 2022
• Study Start: January 1, 2018
• Primary Completion: December 31, 2018
• Study Completion: December 31, 2018
• Last Updated: July 24, 2023

Record last verified: 2023-07

Locations

PA (1)