Comparison of Two Different Approach TAP Block on Pain Management of Laparoscopic Nephrectomy

NCT05188794 | Completed

• 1 other identifier: E1-21-1814
• Study Type: interventional
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

Primary aim is to compare the effectiveness of the posterior approach Transversus abdominis plane block (P-TAP) and the lateral approach Transversus abdominis plane block (L-TAP) technique on the pain management of the laparoscopic nephrectomy in terms of visual analog pain scale and postoperative opioid consumption. Secondary aim is to compare complication rates of the two techniques.

Conditions

Analgesia, Patient-Controlled; Postoperative Pain, Acute

Outcome Measures

Primary Outcomes (8)

• Visual analog pain scale 0

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  at the PACU arrival

• Visual analog pain scale 1

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative first hour

• Visual Analog Pain scale 2

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative second hour

• Visual analog pain scale 6

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative sixth hour

• Visual Analog Pain scale 12

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative 12. hour

• Visual Analog Pain scale 18

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative18. hour

• Visual Analog Pain scale 24

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Postoperative 24. hour

• opioid comsuption

  Patients will be asked about the severity of pain. They will be told that 0 = no pain, 10 = severe pain, and they will be asked to determine a number between 0 and 10 for the severity of pain.

  Within 24 hours postoperatively

Study Arms (2)

group L

ACTIVE COMPARATOR

Lateral transversus abdominis plane(TAP) block

Procedure: lateral tap block

Group P

ACTIVE COMPARATOR

Posterior transversus abdominis plane block

Procedure: posterior tap block

Interventions

lateral tap block PROCEDURE

In the axial plane on the midaxillary line between the subcostal margin and the iliac crest with a linear probe using a 12 cm insulated nerve block needle is advanced in planely from skin, external, and internal oblique muscles to the target of fascial plane between the internal oblique and the transversus abdominis muscles.

group L

posterior tap block PROCEDURE

In the axial plane on the midaxillary line a linear probe using a 12 cm insulated nerve block needle is advanced posteriorly to the most posterior limit of the TAP between the internal oblique and transversus abdominis muscles.

Group P

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASAI-III patients undergoing laparoscopic nephrectomy
• \<BMI\<40

You may not qualify if:

• infection at the block site
• coagulation disorder
• pregnancy
• kidney failure
• liver failure
• heart failure
• allergy to local anesthetics
• patient refusal

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara City Hospital,Bilkent

Ankara, Cankay, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Agnosia; Pain, Postoperative

Condition Hierarchy (Ancestors)

Perceptual Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Postoperative Complications; Pathologic Processes; Pain

Study Officials

• MİYASE SERAP DİKER, DOCTOR

  ANKARA CİTY HOSPİTAL

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Anaestesia and Reanimation Specialist

Study Record Dates

• First Submitted: November 22, 2021
• First Posted: January 12, 2022
• Study Start: January 1, 2022
• Primary Completion: May 1, 2022
• Study Completion: May 15, 2022
• Last Updated: April 5, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)