NCT05188443

Brief Summary

It has become apparent that patients with co-morbidities have an increased risk of mortality from coronarvirus disease 2019 (COVID-19). However, the impact of subclinical respiratory and cardiovascular disease on the outcome of patients with COVID-19 is currently unknown. This observational study will assess the impact of incidental cardiovascular calcification on radiological imaging on the outcomes of patients with COVD-19.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2020

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

January 5, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 12, 2022

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

September 19, 2024

Status Verified

September 1, 2024

Enrollment Period

2.9 years

First QC Date

January 5, 2022

Last Update Submit

September 16, 2024

Conditions

COVID-19Coronary Artery DiseaseCardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

  • All cause mortality

    All cause mortality

    1 month

Secondary Outcomes (1)

  • Cardiovascular mortality

    1 month

Other Outcomes (1)

  • Myocardial infarction

    1 month

Study Arms (1)

COVID-19

Patients tested for COVID-19 with current or previous (last 3 years) radiological imaging

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Positive RT-PCR test for COVID-19 with radiological imaging available within the last 3 years.

You may qualify if:

  • One or more positive RT-PCR test for COVID-19.
  • One or more CT or chest x-ray available performed within the last 3 years

You may not qualify if:

  • No available radiological imaging within the last 3 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Edinburgh

Edinburgh, Scotland, EH16 4SA, United Kingdom

Location

MeSH Terms

Conditions

COVID-19Coronary Artery DiseaseCardiovascular Diseases

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesCoronary DiseaseMyocardial IschemiaHeart DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 5, 2022

First Posted

January 12, 2022

Study Start

August 1, 2020

Primary Completion

July 1, 2023

Study Completion

July 1, 2023

Last Updated

September 19, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Not possible due to data collection method.

Locations

GB(1)