NCT05176171|Unknown
Surface Ablation With Corneal Cross Linking in Mild Keratoconus
Advanced Surface Ablation With Corneal Cross Linking in Mild Keratoconus
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Advanced Surface Ablation With Corneal Cross Linking in Mild Keratoconus
Sponsor study identifier
interventional
50
1 country
1
Study Start
March 5, 2018
Actual (reported)Primary Completion
March 5, 2019
Actual (reported)Study Completion
July 5, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Interventional and comparative prospective study: Sixty-nine eyes (38 patients) suffering from keratoconus (stages 1-2 Amsler-Krumeich classification) will be divided into four groups. The four groups underwent topography- and non-topography-guided PRK with sequential and simultaneous CXL. The main outcome measures will be pre-and postoperative uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (CDVA), manifest refraction, contrast sensitivity, and keratometry
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 5, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 5, 2018
Actual (reported)March 5, 2019
Actual (reported)April 5, 2020
Actual (reported)January 4, 2022
Actual (reported)July 5, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Visual Acuity
Evaluation of the uncorrected visual acuity, best corrected visual acuity, astigmatism, intraocular pressure and endothelial cell loss before and after the last operation.
3 year
For correction of refractive error
To our knowledge, this study is one of the first to compare the visual results of non-topography-guided and topography-guided photorefractive keratectomy (PRK) applying sequential and simultaneous corneal cross-linking (CXL) treatment for keratoconus. Considering recent advances in cross-linking and imaging in keratoconus, the outcomes of this study can lead us to several non-invasive algorithm management options.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Negah Eye Hospital
Tehran, 1544914599, Iran
Azad sanginabadi, PhD
Iran University of Medical Sciences
50 participants (actual enrollment reported by the registry).
First Submitted
April 5, 2020
First Posted
January 4, 2022
Study Start
March 5, 2018
Actual (reported)Primary Completion
March 5, 2019
Actual (reported)Study Completion
July 5, 2023
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
April 18, 2022
Record last verified: 2022-01
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Source: ClinicalTrials.gov.
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