NCT05175534

Brief Summary

The goal of this study is to describe the safety and impact of transesophageal echocardiography in instability episodes during liver transplantation, especially during reperfusion stage. After institutional review board approval, this study was performed in Vall d´Hebron University Hospital including patients undergoing liver transplantation Interventions: peroperative transesophageal echocardiography A transesophageal echocardiography scan was performed in case of hemodynamic instability episodes, and immediately after vascular unclamping. The investigators registered percentatge of patients with diastolic/systolic dysfunction, hypovolemia, vasodilatation, embolism and percentatge of patients with postreperfusion syndrome

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2016

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 30, 2016

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 10, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

June 10, 2020

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

December 8, 2021

Completed
26 days until next milestone

First Posted

Study publicly available on registry

January 3, 2022

Completed
Last Updated

February 21, 2023

Status Verified

February 1, 2023

Enrollment Period

4.3 years

First QC Date

December 8, 2021

Last Update Submit

February 16, 2023

Conditions

Liver Transplant; Complications

Outcome Measures

Primary Outcomes (1)

  • determine the cardiac alterations observed during reperfusion phase

    relationship between cardiac dysfunction and development of post reperfusion syndrome

    during liver transplant

Secondary Outcomes (1)

  • determine the cardiac alterations during episodes of hemodynamic instability

    during liver transplant

Interventions

monitoringPROCEDURE

peroperative transesophageal echocardiography for monitoring in liver transplant surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing liver transplantation

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Susana González Suárez

Barcelona, Catalonia, 08035, Spain

Location

Vall d´Hebron Research Institute VHIR

Barcelona, 08035, Spain

Location

Related Publications (1)

  • Gonzalez-Suarez S, Corbett M, Hernandez-Martinez A. Impact of graft reperfusion on cardiac function assessed by transesophageal echocardiography during liver transplantation: an observational retrospective study. J Clin Monit Comput. 2024 Apr;38(2):301-311. doi: 10.1007/s10877-023-01110-5. Epub 2023 Nov 30.

    PMID: 38032448DERIVED

Study Officials

  • Susana González-Suárez, MD, PhD

    Vall d´Hebron University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 8, 2021

First Posted

January 3, 2022

Study Start

January 30, 2016

Primary Completion

May 10, 2020

Study Completion

June 10, 2020

Last Updated

February 21, 2023

Record last verified: 2023-02

Locations

ES(2)